Prevalence of thyroid diseases in patients with acromegaly: results of an Italian Multi-center Study
Prevalence of thyroid diseases in patients with acromegaly: results of an Italian Multi-center Study
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DOI：
10.1007/bf03343997
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发表时间：
2002-03-01
影响因子：
5.4
通讯作者：
Liuzzi, A
中科院分区：
文献类型：
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作者：
Gasperi, M;Martino, E;Liuzzi, A
肢端肥大症经常与甲状腺疾病的存在有关，但确切的患病率仍有争议。对258例活动性肢端肥大症患者（OGTT后IGF-I水平高且血清GH水平低于2 μ g/l且无抑制）进行了一项意大利多中心研究。对照组为150例无功能和PRL分泌垂体腺瘤患者。258例肢端肥大症患者中有202例（78%）患有甲状腺疾病，其患病率明显高于对照组（27%，p
Acromegaly is frequently associated with the presence of thyroid disorders, however the exact prevalence is still controversial. An Italian multicenter study was performed on 258 patients with active acromegaly (high levels of IGF-I and lack of suppression of serum GH levels below 2 mug/l after an OGTT). The control group was represented by 150 patients affected by non-functioning and PRL-secreting pituitary adenomas. Two hundred and two out of 258 acromegalic patients (78%) were affected by thyroid disorders with a significantly higher prevalence with respect to the control group (27%, p