A randomized, double-blind study to assess if vitamin D treatment affects the outcomes of rehabilitation and balance in hemiplegic patients.
A randomized, double-blind study to assess if vitamin D treatment affects the outcomes of rehabilitation and balance in hemiplegic patients.
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DOI：
10.1589/jpts.30.874
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发表时间：
2018-06-01
影响因子：
--
通讯作者：
Aktas, Ilknur
中科院分区：
文献类型：
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作者：
Sari, Aylin;Durmus, Bekir;Aktas, Ilknur
[目的]探讨补充维生素D对缺血性脑卒中偏瘫患者康复结局及平衡功能的影响。【对象与方法】对132例缺血性脑卒中偏瘫康复住院患者进行维生素D水平检测。因此，132名患者中有86名维生素D水平低，其中72名符合纳入标准并被纳入研究。将患者分为两组：A组（注射300,000 IU维生素D）和B组（肌肉注射生理盐水）。每位患者在基线和第三个月时使用Brunnstrom恢复分期、功能活动量表、改良Barthel指数和Berg平衡量表进行测试。研究结果在两组之间进行了比较。[结果]治疗第3个月结束时，两组患者的Berg平衡量表结果和改良Barthel指数得分差异有统计学意义，而Brunnstrom恢复分期和功能活动量表测试结果差异无统计学意义。【结论】本研究发现，服用维生素D增加了活动水平，加速了平衡恢复，但对行走或运动恢复没有显著影响。这些结果需要更长的随访研究和更多的参与者来证实。
[Purpose] To investigate the effect of vitamin D supplementation on rehabilitation outcomes and balance in patients having hemiplegia due to ischemic stroke. [Subjects and Methods] Vitamin D levels of 132 patients hospitalized for hemiplegia rehabilitation due to ischemic stroke were tested. Consequently, 86/132 patients had low vitamin D levels, 72 of which met the inclusion criteria and were included in the study. Patients were divided into two groups: Group A (injected with 300,000 IU vitamin D), and Group B (injected intramuscularly with saline). Each patient was tested at the baseline and at the third month using the Brunnstrom recovery staging, functional ambulation scale, modified Barthel index, and Berg balance scale. The findings were compared between the groups. [Results] By the end of the third month, The Berg balance scale results and modified Barthel index scores significantly differed between the two groups, whereas Brunnstrom recovery staging and functional ambulation scale test results did not. [Conclusion] This study found that vitamin D administration increased the activity levels and accelerated balance recovery but did not significantly affect ambulation or motor recovery. These results warrant confirmation by longer follow-up studies with a larger number of participants.