Changes in body weight and tuberculosis treatment outcome in Viet Nam

Changes in body weight and tuberculosis treatment outcome in Viet Nam
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DOI:
10.5588/ijtld.12.0369
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发表时间:
2013-01-01
影响因子:
4
通讯作者:
Rieder, H. L.
Rieder, H. L.
中科院分区:
医学4区
文献类型:
--
作者:
Hoa, N. B.;Lauritsen, J. M.;Rieder, H. L.

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环境:越南国家结核病规划,2008年。目的:评估体重变化与结核病(TB)治疗结果之间的关系。方法:分析了来自该国随机选择的30个治疗单位样本的患者的所有治疗卡。结果:在2609名患者中,2506名(96.1%)治疗结果成功。诊断时所有患者的中位体重为46.0 kg(第25和第75个月41-51)。新的痰涂片阳性结核病患者在治疗期间平均增加了2.6公斤。在治疗的前2个月内体重减轻的患者比体重未减轻的患者更有可能获得不成功的结局(OR 4.9,95%CI 3.0-7.9)。当患者体重
SETTING: National Tuberculosis Programme, Viet Nam, 2008.OBJECTIVE: To assess the relationship between changes in body weight and tuberculosis (TB) treatment outcome.METHODS: All treatment cards of patients from a sample of 30 randomly selected treatment units in the country were analysed.RESULTS: Of 2609 patients, 2506 (96.1%) had a successful treatment outcome. The median body weight of all patients at diagnosis was 46.0 kg (25th and 75th percentiles 41-51). New sputum smear-positive TB patients with a successful treatment outcome gained an average of 2.6 kg during treatment. Patients with weight loss during the first 2 months of treatment were more likely to have an unsuccessful outcome than patients without (OR 4.9, 95%CI 3.0-7.9). Patients weighing