Inverse scattering and refraction corrected reflection for breast cancer imaging
Inverse scattering and refraction corrected reflection for breast cancer imaging
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用于乳腺癌成像的逆散射和折射校正反射
DOI：
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发表时间：
2010
期刊：
影响因子：
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通讯作者：
J. Klock
中科院分区：
文献类型：
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作者：
J. Wiskin;D. Borup;S. Johnson;M. Berggren;D. Robinson;J. Smith;J. Chen;Y. Parisky;J. Klock
反射超声 (US) 作为辅助成像方式已有 30 多年的历史。 TechniScan, Inc. 开发了独特的透射和伴随反射算法，用于根据称为温浴超声 (WBU™) 的乳腺断层扫描过程中收集的数据重建图像。传输算法可生成高分辨率、3D、衰减和声速 (SOS) 图像。反射算法基于规范光线追踪，利用 SOS 和衰减重建进行折射校正。折射校正反射算法允许 360 度合成，从而产生反射图像。在 33°C 水浴中扫描整个乳房时，平均需要 8 分钟即可收集必要的数据。本演示介绍了如何通过 3D 透射和反射成像模式算法收集和处理数据。使用两个 NVIDIA® Tesla™ GPU 处理器执行处理，访问 4-TeraByte RAID 上的数据。 WBU™ 图像显示在 DICOM 查看器中，允许注册所有三种模式。几个代表性病例展示了潜在的诊断能力，包括：囊肿、纤维腺瘤和癌。 WBU™ 图像（SOS、衰减和反射模式）与其各自的乳房 X 光照片和标准超声图像一起显示。此外，解剖学研究还比较了尸体乳房的 WBU™ 图像和 MRI 图像。这项创新技术旨在为诊断乳腺疾病提供额外的工具。
Reflection ultrasound (US) has been utilized as an adjunct imaging modality for over 30 years. TechniScan, Inc. has developed unique, transmission and concomitant reflection algorithms which are used to reconstruct images from data gathered during a tomographic breast scanning process called Warm Bath Ultrasound (WBU™). The transmission algorithm yields high resolution, 3D, attenuation and speed of sound (SOS) images. The reflection algorithm is based on canonical ray tracing utilizing refraction correction via the SOS and attenuation reconstructions. The refraction correction reflection algorithm allows 360 degree compounding resulting in the reflection image. The requisite data are collected when scanning the entire breast in a 33° C water bath, on average in 8 minutes. This presentation explains how the data are collected and processed by the 3D transmission and reflection imaging mode algorithms. The processing is carried out using two NVIDIA® Tesla™ GPU processors, accessing data on a 4-TeraByte RAID. The WBU™ images are displayed in a DICOM viewer that allows registration of all three modalities. Several representative cases are presented to demonstrate potential diagnostic capability including: a cyst, fibroadenoma, and a carcinoma. WBU™ images (SOS, attenuation, and reflection modalities) are shown along with their respective mammograms and standard ultrasound images. In addition, anatomical studies are shown comparing WBU™ images and MRI images of a cadaver breast. This innovative technology is designed to provide additional tools in the armamentarium for diagnosis of breast disease.