Prevalence of Helicobacter Pylori Infection Among Patients Undergoing Upper Gastrointestinal Endoscopy in a Medical College Hospital in Kerala, India
Prevalence of Helicobacter Pylori Infection Among Patients Undergoing Upper Gastrointestinal Endoscopy in a Medical College Hospital in Kerala, India
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DOI：
10.4103/2141-9248.122109
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发表时间：
2013-10-01
影响因子：
--
通讯作者：
Sumangala, B.
中科院分区：
文献类型：
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作者：
Adlekha, S.;Chadha, T.;Sumangala, B.
背景：幽门螺杆菌相关性胃炎是发展中国家的一种主要疾病。从慢性胃炎到胃恶性肿瘤的发病率和死亡率都很高。H.幽门螺杆菌感染在不同国家和不同国家、地区之间有很大差异。目的：了解H.内镜检查患者幽门螺杆菌性胃炎及其与胃肠道疾病发展的关系受试者和方法：本研究在印度喀拉拉邦的一所医学院医院进行。对有消化不良症状的患者进行上消化道内镜检查，并对H。pylori感染的病理组织学检查和快速尿素酶试验。H.如果一个或两个诊断测试结果为阳性，则确定为幽门感染。使用Windows 16.0版社会科学统计软件包（SPSS 16;芝加哥，伊利诺伊州，美国）进行数据分析。结果：H. pylori感染率为62.0%（329/530）。H< 50 year age group and >.幽门感染然而，一个统计学上显着的关联H。幽门螺杆菌感染伴内镜检查异常、消化性溃疡和异型增生/癌症。结论：H.在喀拉拉邦的埃尔纳库拉姆区的农村和郊区人口中，幽门螺杆菌感染率显著较高。早期发现和及时治疗对预防严重并发症至关重要。
Background: Helicobacter pylori related gastritis is a major health ailment in developing nations. There is high morbidity and mortality ranging from chronic gastritis to gastric malignancies. Prevalence of H. pylori infection varies markedly from country to country and in a country, region to region. Aim: To study the prevalence of H. pylori gastritis in patients undergoing endoscopy and its association with the development of gastrointestinal diseases. Subjects and Methods: The study was carried out in a Medical College Hospital in Kerala, India. Patients presenting with dyspeptic symptoms were subjected to upper gastrointestinal endoscopy and investigated for H. pylori infection through histopathological examination and rapid urease test of biopsy specimen. Diagnosis of H. pylori infection was made if one or both diagnostic test results were positive. Data analysis was carried out using the statistical package for social sciences, for Windows version 16.0 (SPSS 16; Chicago, IL, USA). Results: H. pylori infection was diagnosed in 62.0% (329/530) of patients screened. There was no statistically significant difference in sex and age related distribution (< 50 year age group and > 50 year age group) of H. pylori infection. However, a statistically significant association of H. pylori infection with the presence of endoscopic abnormalities, peptic ulcer, and dysplasia/cancer was seen. Conclusion: The prevalence of H. pylori infection is significantly high in rural and suburban population of Ernakulam district, Kerala. Early detection and prompt treatment are essential for prevention of serious complications.