Emerging Cancer Therapy: Microbial Approaches and Biotechnological Tools
Emerging Cancer Therapy: Microbial Approaches and Biotechnological Tools
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新兴癌症治疗：微生物方法和生物技术工具
DOI：
10.1002/9780470626528
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发表时间：
2010
期刊：
影响因子：
17.1
通讯作者：
A. Chakrabarty
中科院分区：
文献类型：
--
作者：
A. Fialho;A. Chakrabarty
描述：探索微生物作为抗癌药物的当前和新兴应用当今，癌症患者的治疗选择通常包括手术、放射治疗、免疫治疗和化疗。虽然这些疗法挽救了生命，减少了痛苦和痛苦，但癌症每年仍在世界各地夺走数百万人的生命。近年来，研究人员一直在研究一种新的策略：开发专门攻击癌细胞的微生物和微生物产品。本书通过介绍在癌症治疗中使用微生物和病毒及其产品的最新进展，在新兴的癌症治疗方式中开辟了新的领域。十七章回顾了活微生物、微生物衍生的高、低分子量产品，以及与癌症靶向分子融合的微生物产品的应用。此外，该书还强调了多靶点方法摧毁癌细胞的好处。读者不仅会发现基础和临床研究的结果和意义，而且还会从临床试验中发现令人鼓舞的结果。新兴癌症疗法分为三个部分：第一部分：作为抗癌剂的活/减毒细菌和病毒第二部分：作为抗癌剂的细菌产品第三部分：作为抗癌剂的细菌/细菌产品的专利，章节由微生物、生物技术和癌症研究的领先先驱撰写。建议生物技术专家、微生物学家、临床肿瘤学家、药物化学家和生物化学家使用新兴癌症疗法。读者不仅将了解微生物和生物技术方法在癌症治疗中的巨大潜力，还将发现有效药物发现和开发的新研究方向。
Description: Explores current and emerging applications of microbes as cancer–fighting agents Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. In recent years, researchers have been working on a new strategy: developing microbes and microbial products that specifically attack cancer cells. This book breaks new ground in emerging cancer treatment modalities by presenting recent advances in the use of microorganisms and viruses as well as their products in cancer therapy. Seventeen chapters review the application of live microorganisms, high and low molecular weight products derived from microorganisms, and microbial products fused to cancer–targeting molecules. In addition, the book highlights the benefits of a multi–target approach to destroy cancer cells. Readers will not only discover the results and significance of basic and clinical research, but also encouraging results from clinical trials. Emerging Cancer Therapy is divided into three sections: Section 1: Live/Attenuated Bacteria and Viruses as Anticancer Agents Section 2: Bacterial Products as Anticancer Agents Section 3: Patents on Bacteria/Bacterial Products as Anticancer Agents With chapters written by leading pioneers in microbial, biotech, and cancer research, Emerging Cancer Therapy is recommended for biotechnologists, microbiologists, clinical oncologists, medicinal chemists, and biochemists. Readers will not only learn the tremendous potential of microbial and biotechnological approaches to cancer therapy, but also discover new directions of research for effective drug discovery and development.