Association of intraoperative hypotension with acute kidney injury after liver resection surgery: an observational cohort study.
Association of intraoperative hypotension with acute kidney injury after liver resection surgery: an observational cohort study.
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术中低血压与肝切除术后急性肾损伤的关联：一项观察性队列研究
DOI：
10.1186/s12882-020-02109-9
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发表时间：
2020-11-02
期刊：
影响因子：
2.3
通讯作者：
Zhou Z
中科院分区：
文献类型：
--
作者：
Liao P;Zhao S;Lyu L;Yi X;Ji X;Sun J;Jia Y;Zhou Z
急性肾损伤(AKI)是肝切除术后的主要并发症。本研究的目的是确定肝切除术后AKI的危险因素，以及术中低血压是否与AKI有关。对2017年11月至2019年11月在本院行肝切除术的成人患者(≥18 )进行了回顾分析。≥定义为术后48 小时内血肌酐较术前升高50%。术中持续10分钟以上的最低绝对平均动脉压(MAP) <； 65 。将患者分为急性心肌梗死组和非急性心肌梗死组，并按年龄 ≥ 65 进行分层。对符合纳入和排除标准的796名患者进行了分析。经多因素回归分析，高血压(OR，2.565；P = 0.009)和年龄( ≥ 65 ，OR，2.463；P = 0.008)是急性脑梗塞的危险因素。IOH(OR，3.547；P = 0.012)和接受红细胞计数(OR，3.032；P = 0.036)是65岁 ≥ 患者急性肾功能衰竭的危险因素。高龄 ≥ 65 是术后急性肾功能不全的危险因素，65岁 ≥ 高龄患者术后急性肾功能不全与高龄急性肝损伤相关。补充信息附于本文件10.1186/s12882-020-02109-9。
Acute kidney injury (AKI) is a major complication following liver resection. The aim of this study was to determine the risk factors for AKI after hepatic resection and whether intraoperative hypotension (IOH) was related to AKI. Adult patients (≥ 18 years) undergoing liver resection between November 2017 and November 2019 at our hospital were retrospectively reviewed. AKI was defined as ≥50% increase in serum creatinine from baseline value within 48 h after surgery. IOH was defined as the lowest absolute mean arterial pressure (MAP) < 65 mmHg for more than 10 cumulative minutes during the surgery. Patients were divided into AKI group and non-AKI group, and were stratified by age ≥ 65 years. 796 patients who met our inclusion and exclusion criteria were analyzed. After multivariable regression analysis, the IOH (OR, 2.565; P = 0.009) and age ≥ 65 years (OR, 2.463; P = 0.008) were risk factors for AKI. The IOH (OR, 3.547; P = 0.012) and received red blood cell (OR, 3.032; P = 0.036) were risk factors of AKI in age ≥ 65 years patients. The IOH and age ≥ 65 years were risk factors for postoperative AKI, and IOH was associated with AKI in age ≥ 65 years patients following liver resection. Supplementary information accompanies this paper at 10.1186/s12882-020-02109-9.
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DOI：
10.1186/s13054-016-1352-z
发表时间：
2016-07-04
期刊：
Critical care (London, England)
影响因子：
--
作者：
O'Neal JB;Shaw AD;Billings FT 4th
通讯作者：
Billings FT 4th
影响因子：
2.9
作者：
Ishikawa S;Tanaka M;Maruyama F;Fukagawa A;Shiota N;Matsumura S;Makita K
通讯作者：
Makita K
DOI：
10.1053/j.ajkd.2015.02.338
发表时间：
2015-10
期刊：
American journal of kidney diseases : the official journal of the National Kidney Foundation
影响因子：
--
作者：
James MT;Grams ME;Woodward M;Elley CR;Green JA;Wheeler DC;de Jong P;Gansevoort RT;Levey AS;Warnock DG;Sarnak MJ;CKD Prognosis Consortium
通讯作者：
CKD Prognosis Consortium
影响因子：
3.6
作者：
Hallqvist, Linn;Granath, Fredrik;Bell, Max
通讯作者：
Bell, Max
影响因子：
2.6
作者：
Shirabe, Ken;Kajiyama, Kiyoshi;Maehara, Yoshihiko
通讯作者：
Maehara, Yoshihiko