Wear and damage of articular cartilage with friction against orthopedic implant materials.
Wear and damage of articular cartilage with friction against orthopedic implant materials.
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DOI：
10.1016/j.jbiomech.2015.04.008
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发表时间：
2015-07-16
影响因子：
2.4
通讯作者：
Ateshian GA
中科院分区：
文献类型：
--
作者：
Oungoulian SR;Durney KM;Jones BK;Ahmad CS;Hung CT;Ateshian GA
本研究的目的是测量未成熟的牛关节软骨与用于半关节置换术的玻璃或合金对比时的磨损反应。选择了两种钴铬合金和一种不锈钢合金进行了这些研究。其中一种钴铬合金的表面粗糙度也在监管机构认为可接受的范围内变化。软骨盘的测试配置促进了间质液体加压的丧失，以加速据信发生在半关节成形术中的情况。结果表明，在不锈钢(10 nm粗糙度)和低碳钴铬合金(27 nm粗糙度)上测试的软骨样品比玻璃(10 Nm)和更光滑的低或高碳钴铬(10 Nm)的软骨样品受到的损伤要大得多。产生最大损伤的两种材料也表现出更高的平衡摩擦系数。软骨损伤主要发生在浅切向区和中间过渡区之间的界面处的剥离形式，关节表面磨粒磨损的证据要少得多。这些结果表明，摩擦载荷造成的软骨损伤是由于亚表面疲劳破坏导致的分层。植入材料的表面化学成分和表面粗糙度对组织损伤有显著影响，即使在使用满足法规要求的材料和粗糙度时也是如此。
The objective of this study was to measure the wear response of immature bovine articular cartilage tested against glass or alloys used in hemiarthroplasties. Two cobalt chromium alloys and a stainless steel alloy were selected for these investigations. The surface roughness of one of the cobalt chromium alloys was also varied within the range considered acceptable by regulatory agencies. Cartilage disks were tested in a configuration that promoted loss of interstitial fluid pressurization to accelerate conditions believed to occur in hemiarthroplasties. Results showed that considerably more damage occurred in cartilage samples tested against stainless steel (10 nm roughness) and low carbon cobalt chromium alloy (27 nm roughness) compared to glass (10 nm) and smoother low or high carbon cobalt chromium (10 nm). The two materials producing the greatest damage also exhibited higher equilibrium friction coefficients. Cartilage damage occurred primarily in the form of delamination at the interface between the superficial tangential zone and the transitional middle zone, with much less evidence of abrasive wear at the articular surface. These results suggest that cartilage damage from frictional loading occurs as a result of subsurface fatigue failure leading to the delamination. Surface chemistry and surface roughness of implant materials can have a significant influence on tissue damage, even when using materials and roughness values that satisfy regulatory requirements.