Epithelial Contractility: A Crowning Achievement.

Epithelial Contractility: A Crowning Achievement.
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上皮收缩性:一项至高无上的成就。

DOI:
10.1016/j.devcel.2016.03.017
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发表时间:
2016
期刊:
影响因子:
11.8
通讯作者:
Martin,AdamC
Martin,AdamC
中科院分区:
生物学1区
文献类型:
--
作者:
Jodoin,JeanneN;Martin,AdamC

文献摘要

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上皮细胞通过粘附连接传递收缩力,介导凋亡细胞的挤出等形态学变化。在本期发育细胞中,Michael及其同事(2016)表明肌动蛋白结合蛋白Coronin在肌动蛋白细胞骨架重组和与连接点的关联中起着关键作用,以促进收缩性。
Epithelial cells transmit contractile force with adherens junctions to mediate morphological changes like the extrusion of apoptotic cells. In this issue ofDevelopmental Cell, Michael and colleagues (2016) show that the actin binding protein Coronin plays a critical role in actin cytoskeleton reorganization and association with junctions to promote contractility.