Late-stage adult respiratory distress syndrome caused by severe acute respiratory syndrome: Abnormal findings at thin-section CT
Late-stage adult respiratory distress syndrome caused by severe acute respiratory syndrome: Abnormal findings at thin-section CT
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DOI：
10.1148/radiol.2303030894
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发表时间：
2004-02-01
期刊：
影响因子：
19.7
通讯作者：
Ahuja, AT
中科院分区：
文献类型：
--
作者：
Joynt, GM;Antonio, GE;Ahuja, AT
目得：目的：探讨重症监护病房中严重急性呼吸综合征（SARS）所致成人呼吸窘迫综合征（ARDS）晚期患者的薄层CT表现。评价图像的磨玻璃样混浊、实变、间质增厚、纤维化证据和任何其他异常。患者的记录进行了审查，相关的呼吸和呼吸参数，总类固醇剂量，和outcomewere recorded.Results：所有患者接受高剂量脉冲甲基强的松龙（最小，2.5克总），和所有接受通气的患者接受低压，低容量通气。5例患者接受长期机械通气（超过14天），1例接受72小时通气，2例患者未接受通气。3名患者死亡，4人出院，1人继续需要通气。所有8例患者的CT均显示磨玻璃影和间质增厚。6例患者出现实变。3例患者有纤维化证据。接受长期通气的患者、接受短期通气的患者和未接受通气的患者在CT时的肺部变化相似。肺囊肿，其中大部分是小的（
PURPOSE: To evaluate thin-section computed tomographic (CT) abnormalities in patients in the intensive care unit during the late stage of adult respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome (SARS).MATERIALS AND METHODS: Eight patients in the late stage of ARDS (ie, more than 2 weeks after onset) were imaged with thin-section CT. Images were evaluated for ground-glass opacification, consolidation, interstitial thickening, evidence of fibrosis, and any other abnormalities. Patient records were reviewed, and relevant respiratory and ventilatory parameters, total steroid dose, and outcome were recorded.RESULTS: All patients received high-dose pulse methylprednisolone (minimum, 2.5 g total), and all patients who received ventilation received low-pressure, low-volume ventilation. Five patients received prolonged mechanical ventilation (for more than 14 days), one received ventilation for 72 hours, and two patients did not receive ventilation. Three patients died, four were discharged from the hospital, and one continued to require ventilation. Ground-glass opacification and interstitial thickening were present at CT in all eight patients. Consolidation was present in six patients. Three patients had evidence of fibrosis. Patients who received long-term ventilation, those who received short-term ventilation, and those who did not receive ventilation had similar pulmonary changes at CT. Pulmonary cysts, most of which were small (