Decision-making deficits of Korsakoff patients in a new gambling task with explicit rules: Associations with executive functions
Decision-making deficits of Korsakoff patients in a new gambling task with explicit rules: Associations with executive functions
复制标题
DOI：
10.1037/0894-4105.19.3.267
复制
发表时间：
2005-05-01
期刊：
影响因子：
2.4
通讯作者：
Markowitsch, HJ
中科院分区：
文献类型：
--
作者：
Brand, M;Fujiwara, E;Markowitsch, HJ
赌博任务中的风险决策所反映的决策缺陷与各种神经和精神病人群的额叶功能障碍有关。问题仍然是决策障碍是否与执行功能有关。作者开发了一种新的赌博任务，即骰子游戏任务，具有明确且稳定的强化和惩罚规则，以研究明确决策情境下执行功能与冒险行为之间的关系。使用骰子游戏任务和神经心理学测试电池对 35 名科尔萨科夫酗酒患者和 35 名健康对照样本进行了检查。结果表明，科尔萨科夫患者在这种明确的决策任务中受到严重损害，并且这些障碍与特定的执行功能相关。
Decision-making deficits reflected by risky decisions in gambling tasks have been associated with frontal lobe dysfunctions in various neurologic and psychiatric populations. The question remains whether decision-making impairments are related to executive functions. The authors developed a new gambling task, the Game of Dice Task, with explicit and stable rules for reinforcement and punishment, to investigate relations between executive functions and risk-taking behavior in an explicit decision-making situation. A sample of 35 alcoholic Korsakoff patients and 35 healthy controls was examined with the Game of Dice Task and a neuropsychological test battery. Results show that Korsakoff patients are strongly impaired in this explicit decision-making task and that these disturbances are correlated with specific executive functions.