Acute decompensated heart failure syndromes (ATTEND) registry. A prospective observational multicenter cohort study: Rationale, design, and preliminary data
Acute decompensated heart failure syndromes (ATTEND) registry. A prospective observational multicenter cohort study: Rationale, design, and preliminary data
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DOI：
10.1016/j.ahj.2010.03.019
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发表时间：
2010-06-01
影响因子：
4.8
通讯作者：
Takano, Teruo
中科院分区：
文献类型：
--
作者：
Sato, Naoki;Kajimoto, Katsuya;Takano, Teruo
急性心力衰竭综合征（Acute heart failure syndrome， AHFS）在未来可能会增加，AHFS患者的高再入院率是西方国家的一个重要问题。然而，在亚太地区发表的关于AHFS的流行病学研究很少。由于AHFS是异质性的，AHFS的特征、临床特征和管理应在流行病学研究中加以阐明。急性失代偿性心力衰竭综合征（ATTEND）登记是一项在日本进行的前瞻性、观察性、多中心队列研究，是亚太地区首个AHFS流行病学研究。本研究旨在探讨AHFS的以下几个方面：(1)注册表允许基于患者的数据收集，以精确评估患者特征和短期结果，包括再入院率；(2)可以对临床评估进行确认，并创建新的临床评估；(3)反馈可以修改临床管理指南。本报告根据本研究收集的初步数据，描述了日本AHFS患者的临床特征，以及这些患者与西方国家患者特征的异同。尽管大多数患者的特征与西方研究报告没有什么不同，但本研究也有一些独特的发现，包括出院时使用卡立肽（69.4%）和血管紧张素II受体阻滞剂（53.9%）的比例较高，住院时间较长（中位21天）。出席登记的目的是提供有价值的信息，以澄清AHFS患者的特点，以改善他们的管理。[J] .中国生物医学工程学报；2010;31(2):349 - 355。
Acute heart failure syndromes (AHFS) are likely to increase in the future, and the high readmission rate of patients with AHFS is an important issue in Western countries. However, there are very few published epidemiological studies on AHFS in the Asia Pacific region. Because AHFS are heterogeneous, the characteristics, clinical profile, and management of AHFS should be clarified in an epidemiological study. The acute decompensated heart failure syndromes (ATTEND) registry is a prospective, observational, multicenter cohort study being performed in Japan and is the first epidemiological study of AHFS in the Asia Pacific region. This study is designed to investigate several aspects of AHFS as follows: (1) the registry allows patient-based data collection for precise evaluation of patient characteristics and short-term outcomes, including the readmission rate; (2) confirmation of clinical assessments can be performed, and new clinical assessments can be created; and (3) feedback allows the modification of guidelines for clinical management. The present report describes the clinical characteristics of patients with AHFS in Japan based on the preliminary data collected in this study, and the similarities and differences in characteristics of these patients compared with those in Western countries. Although most of the patient characteristics did not differ from those reported in Western studies, there are some unique findings in this study, including a high rate of treatment with carperitide (69.4%) and angiotensin II receptor blockers (53.9%) at discharge and a longer hospital stay (median 21 days). The ATTEND registry is designed to provide valuable information to clarify the characteristics of patients with AHFS to improve their management. (Am Heart J 2010; 159: 949-955.e1.)