Abnormal number cell division of human thyroid anaplastic carcinoma cell line, SW 1736.
Abnormal number cell division of human thyroid anaplastic carcinoma cell line, SW 1736.
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DOI：
10.1016/j.dib.2015.09.030
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发表时间：
2015-12
期刊：
影响因子：
1.2
通讯作者：
Manome Y
中科院分区：
文献类型：
--
作者：
Ikeda K;Tachibana T;Suzuki Y;Fujioka K;Takeyama H;Manome Y
细胞分裂是细胞生物学中最重要的生理事件，在一个细胞周期中，母细胞通常分裂为两个子细胞。我们观察到一个到四个细胞分裂过程中的活的SW 1736人甲状腺未分化癌细胞转染质粒表达的杂合蛋白的绿色荧光蛋白和组蛋白2B（质粒eGFP-H2 B）的成像。对图像的分析显示，一个母细胞分裂成四个子细胞。其中一个异常分裂的子细胞随后形成了一个双核细胞。
Cell division, during which a mother cell usually divides into two daughter cells during one cell cycle, is the most important physiological event of cell biology. We observed one-to-four cell division during imaging of live SW1736 human thyroid anaplastic carcinoma cells transfected with a plasmid expressing the hybrid protein of green fluorescent protein and histone 2B (plasmid eGFP-H2B). Analysis of the images revealed a mother cell divided into four daughter cells. And one of the abnormally divided daughter cells subsequently formed a dinucleate cell.