Multiple Sclerosis in Children: Current and Emerging Concepts.
Multiple Sclerosis in Children: Current and Emerging Concepts.
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DOI：
10.1055/s-0040-1703000
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发表时间：
2020-04
影响因子：
2.7
通讯作者：
Makhani N
中科院分区：
文献类型：
--
作者：
Brenton JN;Kammeyer R;Gluck L;Schreiner T;Makhani N
儿童多发性硬化症正在得到越来越多的认识和诊断。在过去的几年中，在诊断儿童多发性硬化症、识别新的遗传和环境危险因素、描述潜在的免疫生物学、表征影像学结果以及实施新的治疗策略方面取得了进展。在这篇评论中，我们讨论了这些进展。持续的国际合作将有助于未来对儿童多发性硬化症决定因素和新治疗方案的研究。
Multiple sclerosis is being increasingly recognized and diagnosed in children. In the past several years, advances have been made in diagnosing multiple sclerosis in children, identifying new genetic and environmental risk factors, delineating underlying immunobiology, characterizing imaging findings, and implementing new treatment strategies. In this review, we discuss these advances. Future research into the determinants of multiple sclerosis in children and into new treatment options will be aided by continued international collaboration.