Frequency characteristics of long-term heart rate variability during constant-routine protocol
Frequency characteristics of long-term heart rate variability during constant-routine protocol
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DOI：
10.1152/ajpregu.00661.2002
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发表时间：
2003-07-01
影响因子：
2.8
通讯作者：
Yamamoto, Y
中科院分区：
文献类型：
--
作者：
Aoyagi, N;Ohashi, K;Yamamoto, Y
体力活动、食物摄入和昼夜节律等行为因素对人类长期心率变异性 (HRV) 的影响仍知之甚少。因此，我们使用包括同步核心体温 (CBT) 校正在内的恒定常规方案研究了它们对 HRV 的影响。七名健康受试者完成了恒定常规和每日常规方案，在此期间持续监测 HRV 和 CBT。在持续的日常活动中，受试者保持半卧姿势清醒 27 小时，进行最少的体力活动；每 2 小时提供少量等热量膳食。在日常生活中，受试者正常生活。使用基于快速傅里叶变换的通用光谱分析来分析数据；还使用粗粒度频谱分析来消除由于原始 HRV 和没有昼夜节律和/或低频超电分量的 CBT 校正 HRV 的定期膳食而产生的周期性。结果表明：1）恒定常规和日常中的 HRV 功率谱在高于 10（-3.5）Hz 的频率下具有相似的幂律标度，而 2）低于该交叉频率，恒定常规中的 HRV 小于日常常规中的 HRV，并且差异在 < 10（-4）Hz 时变得显着（P < 0.05），3）粗粒度频谱分析消除了基于通用频谱分析的 HRV 频谱中饮食引起的峰值恒定的例程并强调类似于10（-3.5）Hz的交叉，并且4）CBT校正没有改变结果。在频率低于 10(-3.5) Hz（周期 > 1 小时）时，HRV 受行为因素的强烈影响；高于该交叉频率，HRV 与行为无关，可能反映了内在的调节系统。
The effects of such behavioral factors as physical activity, food intake, and circadian rhythm on long-term heart rate variability (HRV) in humans remain poorly understood. We therefore studied their effects on HRV using a constant-routine protocol that included simultaneous core body temperature (CBT) correction. Seven healthy subjects completed the constant-routine and daily-routine protocols, during which HRV and CBT were continuously monitored. During the constant routine, subjects were kept awake for 27 h in a semirecumbent posture with minimal physical activity; small isocaloric meals were provided every 2 h. During the daily routine, subjects carried on their lives normally. Data were analyzed using generic spectral analysis based on a fast Fourier transform; coarse-graining spectral analysis was also used to eliminate periodicity due to the regular meals for raw HRV and for the CBT-corrected HRV without circadian and/or low-frequency ultradian components. The results showed that 1) the power spectra of HRV in the constant routine and daily routine had similar power-law scalings at frequencies above similar to10(-3.5) Hz, while 2) below that crossover frequency, HRV was smaller in the constant routine than in the daily routine, with the difference becoming significant (P < 0.05) at < 10(-4) Hz, 3) coarse-graining spectral analysis eliminated diet-induced peaks in generic spectral analysis-based HRV spectra during the constant routine and emphasized the crossover at similar to10(-3.5) Hz, and 4) CBT correction did not alter the results. Below a frequency of similar to10(-3.5) Hz (a period > 1 h), HRV is strongly influenced by behavioral factors; above that crossover frequency, HRV is behavior independent, possibly reflecting an intrinsic regulatory system.