Storage capacity of subcutaneous fat in Japanese adults
Storage capacity of subcutaneous fat in Japanese adults
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DOI：
10.1038/ejcn.2014.292
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发表时间：
2015-08-01
影响因子：
4.7
通讯作者：
Nakai, M.
中科院分区：
文献类型：
--
作者：
Sato, S.;Demura, S.;Nakai, M.
背景技术背景：在我们以前的研究的基础上，研究了内脏脂肪面积（VFA）和躯干区域脂肪量百分比之间的非线性关系，我们假设存在一些皮下脂肪的储存能力。本研究以791名日本成年男性和563名女性的皮下脂肪面积（SFA）和VFA为基础，对内脏脂肪肥胖（VO）分为VO（VFA >= 100 cm（2））组和无VO（NVO）组，以SFA为因变量，VFA为自变量进行回归分析。为了从统计学上确定皮下脂肪堆积的最佳临界点，我们将VO组的临界点从50-150 cm（2）改为10 cm（2）增量，并证实了每个肥胖组SFA和VFA之间相关性的显著性，NVO和VO组之间相关性的统计学差异，以及使用估计值的标准误差的两条回归线的拟合优度。这些分析进行了每个性别和年龄（= 65岁）group.RESULTS：皮下脂肪积累的临界点出现在以下临界点VFA：130 cm（2）在= 65岁的男性和100 cm（2）在两个女性group.CONCLUSIONS：这些结果表明存在一些储存能力的皮下脂肪。作为进一步的应用，这些发现可能有助于改善肥胖相关疾病的风险评估。
BACKGROUND: On the basis of our previous study, which examined the nonlinear relationship between visceral fat area (VFA) and percent regional fat mass in the trunk, we hypothesise the presence of some storage capacity of subcutaneous fat. This study aimed to examine the storage capacity of subcutaneous fat on the basis of subcutaneous fat area (SFA) and VFA in 791 Japanese adult males and 563 females.METHODS: Regression analyses by using SFA as a dependent variable and VFA as an independent variable were performed for each group classified by visceral fat obesity (VO): VO (VFA >= 100 cm(2)) and the no-VO (NVO) groups. To statistically identify an optimal critical point for subcutaneous fat accumulation, we changed the cutoff point for the VO group from 50-150 cm(2) in 10-cm(2) increments and confirmed the significance of the correlation between SFA and VFA for each obesity group, the statistical difference in correlations between NVO and VO groups, and the goodness of fit for the two regression lines using the standard error of estimation values. These analyses were conducted for each sex and age (= 65 years) group.RESULTS: The critical point for subcutaneous fat accumulation appears at the following cutoff points of VFA: 130 cm(2) in = 65-year-old males and 100 cm(2) in both female groups.CONCLUSIONS: These results suggest the presence of some storage capacity of subcutaneous fat. As a further application, these findings may serve to improve the risk assessment of obesity-related diseases.