Genetic feminization of pheromones and its behavioral consequences in Drosophila males
Genetic feminization of pheromones and its behavioral consequences in Drosophila males
复制标题
DOI：
10.1126/science.276.5318.1555
复制
发表时间：
1997-06-06
期刊：
影响因子：
56.9
通讯作者：
Jallon, JM
中科院分区：
文献类型：
--
作者：
Ferveur, JF;Savarit, F;Jallon, JM
信息素是种内重要的化学信号，对配偶的吸引和辨别很重要，在果蝇中，动物表皮表面的碳氢化合物在它们的发生和作用上都具有性别二型性：雌性特有的分子刺激雄性兴奋，而主要的雄性特有分子倾向于抑制雄性兴奋，雄性产生的信息素混合物的完全女性化是通过在成虫卵母细胞(皮层下腹部细胞)中靶向表达转换基因或在早期想象生命中普遍表达而诱导的。由此产生的果蝇通常表现出雄性异性恋倾向，但会引发其他雄性果蝇的同性恋求爱。
Pheromones are intraspecific chemical signals important for mate attraction and discrimination, In the fruit fly Drosophila melanogaster, hydrocarbons on the cuticular surface of the animal are sexually dimorphic in both their occurrence and their effects: Female-specific molecules stimulate male sexual excitation, whereas the predominant male-specific molecule tends to inhibit male excitation, Complete feminization of the pheromone mixture produced by males was induced by targeted expression of the transformer gene in adult oenocytes (subcuticular abdominal cells) or by ubiquitous expression during early imaginal life. The resulting flies generally exhibited male heterosexual orientation but elicited homosexual courtship from other males.