Neck proprioceptive inputs to primate vestibular nucleus neurons
Neck proprioceptive inputs to primate vestibular nucleus neurons
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DOI：
10.1007/s002210000542
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发表时间：
2000-12-01
影响因子：
2
通讯作者：
McCrea, RA
中科院分区：
文献类型：
--
作者：
Gdowski, GT;McCrea, RA
通过记录松鼠猴颈部旋转时次级水平管相关神经元的反应，研究了颈部本体感受信号在前庭神经核信号处理中的作用。被动颈部旋转引起的反应，而头部在空间中保持静止进行了比较被动全身旋转和强迫旋转的头上的躯干引起的反应。大多数神经元（76%; 45/59）对颈部旋转敏感。颈部本体感受性输入的性质和强度各不相同，通常与前庭输入呈线性组合。在大多数情况下（94%），颈部本体感受输入的方向是“拮抗”或“互惠”相对于前庭敏感性，因此，减少前庭反应期间，头对躯干旋转。不同类型的前庭神经元接受不同类型的本体感受输入。放电行为与眼睛位置相关的神经元（位置前庭暂停神经元和位置前庭神经元）通常对头部相对于躯干的位置敏感。对头部位置的敏感性通常与神经元对眼睛位置的敏感性处于同一方向。非眼动相关神经元和眼头速度神经元表现出最强的敏感性，被动颈部旋转，并有信号，最好的颈部速度相关。结果表明，颈部本体感受输入在塑造灵长类动物前庭核的输出及其对姿势、注视和感知的贡献中起着重要作用。
The contribution of neck proprioceptive signals to signal processing in the vestibular nucleus was studied by recording responses of secondary horizontal canal-related neurons to neck rotation in the squirrel monkey. Responses evoked by passive neck rotation while the head was held stationary in space were compared with responses evoked by passive whole body rotation and by forced rotation of the head on the trunk. Most neurons (76%; 45/59) were sensitive to neck rotation. The nature and strength of neck proprioceptive inputs varied and usually combined linearly with vestibular inputs. In most cases (94%), the direction of the neck proprioceptive input was "antagonistic" or "reciprocal" with respect to vestibular sensitivity and, consequently, reduced the vestibular response during; head-on-trunk rotation. Different types of vestibular neurons received different types of proprioceptive input. Neurons whose firing behavior was related to eye position (position-vestibular-pause neurons and position-vestibular neurons) were often sensitive to the position of the head with respect to the trunk. The sensitivity to head position was usually in the same direction as the neuron's eye position sensitivity. Non-eye-movement related neurons and eye-head-velocity neurons exhibited the strongest sensitivity to passive neck rotation and had signals that were best related to neck velocity. The results suggest that neck proprioceptive inputs play an important role in shaping the output of the primate vestibular nucleus and its contribution to posture, gaze and perception.