Molecular cloning and expression of alpha parvalbumin in the guinea pig cochlea.
Molecular cloning and expression of alpha parvalbumin in the guinea pig cochlea.
复制标题
豚鼠耳蜗中α小白蛋白的分子克隆和表达。
DOI：
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发表时间：
1995
期刊：
影响因子：
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通讯作者：
C. Hamel
中科院分区：
文献类型：
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作者：
A. Soto;M. Cluzel;N. Renard;C. Ripoll;M. Lavigne;M. Eybalin;C. Hamel
We have cloned and sequenced an alpha parvalbumin cDNA from the guinea pig cochlea. The deduced amino acid sequence shows greater identity with the rabbit sequence (86.3%) than with other mammalian sequences (< 82%). Using in situ hybridization and immunohistochemistry, alpha parvalbumin mRNA and protein were found in primary auditory neurons and inner hair cells, in agreement with RT-PCR data showing alpha parvalbumin mRNA expression in the spiral ganglion and the organ or Corti.
