Intraoperative bile duct visualization using near-infrared hyperspectral video imaging
Intraoperative bile duct visualization using near-infrared hyperspectral video imaging
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DOI：
10.1016/j.amjsurg.2007.05.044
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发表时间：
2008-04-01
影响因子：
3
通讯作者：
Livingston, Edward
中科院分区：
文献类型：
--
作者：
Zuzak, Karel J.;Naik, Sabira C.;Livingston, Edward
背景资料：目前胆囊切除术中胆道系统成像的方法是繁琐的，不能消除胆管损伤的风险。我们描述了一种方法，术中胆道成像，这将使外科医生看到通过肝十二指肠韧带和可视化的前放置biliary system.Methods：腹腔镜功能，近红外，高光谱成像系统的建立。反射光通过一个液晶滤光片，该滤光片在近红外光谱（650-1，100 nm）中连续可调。光谱图像数据从腹腔镜手术图像收集到阵列检测器上，所述阵列检测器被格式化为三维高光谱数据立方体，所述三维高光谱数据立方体具有在x-y平面中的空间分辨图像和在z平面中的波长数据。解卷积和颜色编码的空间和光谱信息提供了一个图像代表固有的化学性质的成像tissue.Results：猪胆管结构的图像。常见的管道反射光谱显示在930 nm处的特征脂肩和在970 nm处的强水峰。静脉结构在760 nm（脱氧血红蛋白）、800 nm（氧合血红蛋白）和970 nm（水）处具有吸收峰。动脉血管在800 nm和970 nm的吸收峰，这将是预期的氧合血红蛋白和water.Conclusions：我们已经设计并构建了一个设备，以显着提高术中胆道成像。该系统应使外科医生能够透过肝十二指肠韧带看到前方的胆道系统，而不需要像术中胆管造影那样解剖胆囊管。由于在进行任何解剖之前可以看到胆道系统，因此这种三维成像技术具有根除胆管损伤的潜力。(c)2008年爱思唯尔公司All rights reserved.
Background: Current methodologies for imaging the biliary system during cholecystectomy are cumbersome and do not eliminate the risk of bile duct injury. We describe an approach to intraoperative biliary imaging that will enable surgeons to see through the hepatoduodenal ligament and visualize the anteriorly placed biliary system.Methods: A laparoscopic-capable, near-infrared, hyperspectral imaging system was built. Reflected light passes through a liquid crystal filter that is continuously tunable in the near-infrared spectrum (650-1,100nm). Spectroscopic image data are collected from laparoscopic surgery images onto array detectors formatted into a 3-dimensional hyperspectral data cube having spatially resolved images in the x-y plane and wavelength data in the z plane. Deconvoluting and color-coding the spatial and spectral information provides an image representative of inherent chemical properties to the imaged tissue.Results: Images of porcine biliary structures were obtained. The common duct-reflected spectra displayed a characteristic lipid shoulder at 930 nm and a strong water peak at 970 nm. Venous structures had absorption peaks at 760 nm (deoxyhemoglobin), 800 nm (oxyhemoglobin), and 970 nm (water). Arterial vessels had absorption peaks at 800 nm and 970 nm that would be expected for oxyhemoglobin and water.Conclusions: We have designed and constructed a device to significantly enhance intraoperative biliary imaging. This system should enable surgeons to see through the hepatoduodenal ligament and image the anteriorly placed biliary system without the need for dissection of the cystic duct, as is needed with intraoperative cholangiography. Because the biliary system can be seen before any dissection is performed, this dimensional imaging technology has the potential for eradicating bile duct injury. (c) 2008 Elsevier Inc. All rights reserved.