Electrochemical Method for the Determination of Enantiomeric Excess of Binol Using Redox-Active Boronic Acids as Chiral Sensors
Electrochemical Method for the Determination of Enantiomeric Excess of Binol Using Redox-Active Boronic Acids as Chiral Sensors
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DOI：
10.1021/ja103462x
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发表时间：
2010-07-07
影响因子：
15
通讯作者：
Tucker, James H. R.
中科院分区：
文献类型：
--
作者：
Mirri, Giorgio;Bull, Steven D.;Tucker, James H. R.
手性二茂铁基硼酸与 (R)- 和 (S)-Binol 相互作用，形成两种表现出显着不同的复合物。二茂铁基电极电势。原则上可以利用氧化还原行为的这种差异来证明对映体混合物中对映体过量的高水平可以使用电化学方法进行定量和读出。
A chiral ferrocene-based boronic acid interacts with (R)- and (S)-Binol to form two complexes that exhibit significantly different. ferrocene-based electrode potentials. This difference in redox behavior can be exploited to demonstrate in principle how high levels of enantiomeric excess in a mixture of enantiomers can be quantified and read-out using an electrochemical method.