ANALYSIS OF DISCRIMINATION MECHANISMS IN THE MAMMALIAN OLFACTORY SYSTEM USING A MODEL NOSE
ANALYSIS OF DISCRIMINATION MECHANISMS IN THE MAMMALIAN OLFACTORY SYSTEM USING A MODEL NOSE
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DOI：
10.1038/299352a0
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发表时间：
1982-01-01
期刊：
影响因子：
64.8
通讯作者：
DODD, G
中科院分区：
文献类型：
--
作者：
PERSAUD, K;DODD, G
嗅觉表现出对气味的高度敏感性和对它们的高度区分1。我们建议，复杂的气味混合物含有不同比例的气味，而不需要高度专业化的外周受体之间进行精细的区分，嗅觉系统利用功能检测使用广泛调谐的受体细胞组织在一个收敛的神经元通路。作为这个假设的测试，我们已经构建了一个电子鼻使用半导体传感器，并纳入我们的建议的设计特点。我们在这里报告说，这种设备可以重复区分各种各样的气味，其性质表明，在嗅觉系统中的歧视，可以实现不使用高度特异性的受体。
Olfaction exhibits both high sensitivity for odours and high discrimination between them1. We suggest that to make fine discriminations between complex odorant mixtures containing varying ratios of odorants without the necessity for highly specialized peripheral receptors, the olfactory systems makes use of feature detection using broadly tuned receptor cells organized in a convergent neurone pathway. As a test of this hypothesis we have constructed an electronic nose using semiconductor transducers and incorporating design features suggested by our proposal. We report here that this device can reproducibly discriminate between a wide variety of odours, and its properties show that discrimination in an olfactory system could be achieved without the use of highly specific receptors.