Amplification of enantiomeric concentrations under credible prebiotic conditions
Amplification of enantiomeric concentrations under credible prebiotic conditions
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DOI：
10.1073/pnas.0605863103
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发表时间：
2006-08-29
影响因子：
11.1
通讯作者：
Levine, Mindy S.
中科院分区：
文献类型：
--
作者：
Breslow, Ronald;Levine, Mindy S.
通过两次连续蒸发将D-或L-苯丙氨酸的对映体过量（ee）低至1%的溶液放大至90%ee（95/5比率）以沉淀外消旋物。在生命起源前的地球上，这样的过程可能会导致一种机制，通过这种机制，陨石手性α-烷基氨基酸可以形成生物学开始所需的高ee值溶液。
Solutions with as little as 1% enantiomeric excess (ee) Of D- or L-phenylalanine are amplified to 90% ee (a 95/5 ratio) by two successive evaporations to precipitate the racemate. Such a process on the prebiotic earth could lead to a mechanism by which meteoritic chiral alpha-alkyl amino acids could form solutions with high ee values that were needed for the beginning of biology.