Influence of colostrum intake on piglet survival and immunity
Influence of colostrum intake on piglet survival and immunity
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DOI：
10.1017/s175173111100067x
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发表时间：
2011-10-01
期刊：
影响因子：
3.6
通讯作者：
Prunier, A.
中科院分区：
文献类型：
--
作者：
Devillers, N.;Le Dividich, J.;Prunier, A.
对40窝526头仔猪从出生到分娩后24小时（T（24））的初乳摄入量进行了估计。在T（24）时测定每窝6头仔猪的血浆免疫球蛋白G（IgG）、乳酸盐、葡萄糖和皮质醇浓度。还在断奶时（28天）对相同仔猪测定血浆IgG浓度。在T（24）时测量所有仔猪的直肠温度。记录死亡率直至断奶，并对断奶前死亡的仔猪和断奶时仍存活的仔猪进行比较。断奶前死亡的仔猪与断奶时仍存活的仔猪相比，出生体重较低，初乳摄入量较低，出生和T（24）之间的体重增加较低，T（24）时的直肠温度较低，血浆皮质醇浓度较高，血浆IgG和葡萄糖浓度较低。此外，在断奶前死亡的仔猪中，有较高比例的仔猪在出生后难以进行第一次呼吸，并受到八字腿的影响。考虑到所有仔猪，在T（24）时，初乳摄入量与直肠温度和血浆葡萄糖浓度呈正相关，与血浆皮质醇浓度呈负相关。T（24）时血浆IgG浓度与初乳摄入量、初乳中IgG浓度、出生体重和出生秩次有关（P < 0.0001）。断奶时血浆IgG浓度与T（24）时血浆IgG浓度相关（r = 0.54; P < 0.0001），与初乳摄入量相关（r = 0.32; P < 0.0001）。最后，体重是由初乳摄入量、出生体重和6周龄前的年龄解释的（P < 0.0001）。这些结果表明，初乳的摄入量是通过提供能量和免疫保护仔猪生存的主要决定因素，并对仔猪的生长和免疫具有潜在的长期影响。
Colostrum intake from birth to 24 h after the onset of parturition (T(24)) was estimated for 526 piglets from 40 litters. Plasma concentrations of immunoglobulin G (IgG), lactate, glucose and cortisol were determined at T(24) for six piglets per litter. Plasma IgG concentration was also assayed at weaning (28 days) on the same piglets. Rectal temperature was measured at T(24) on all piglets. Mortality was recorded until weaning and comparisons were made between piglets that died before weaning and those that were still alive at weaning. The piglets that died before weaning had lower birth weight, lower colostrum intake, lower weight gain between birth and T(24), and had a lower rectal temperature, higher plasma cortisol concentration and lower plasma IgG and glucose concentrations at T(24) than piglets still alive at weaning. In addition, a higher proportion of piglets that died before weaning had difficulty taking their first breath after birth and were affected by splayleg. Considering all piglets, colostrum intake was positively related to rectal temperature and plasma glucose concentration and negatively related to plasma cortisol concentration at T(24). Plasma IgG concentration at T(24) was explained by colostrum intake, IgG concentration in the ingested colostrum, birth weight and birth rank (P < 0.0001). Plasma IgG concentration at weaning was related to plasma IgG concentration at T(24) (r = 0.54; P < 0.0001) and to colostrum intake (r = 0.32; P < 0.0001). Finally, body weight was explained by colostrum intake, birth weight and age until 6 weeks of age (P < 0.0001). These results show that colostrum intake is the main determinant of piglet survival through provision of energy and immune protection and has potential long-term effects on piglet growth and immunity.