Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994
Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994
复制标题
DOI：
10.1093/ajcn/76.1.187
复制
发表时间：
2002-07-01
影响因子：
7.1
通讯作者：
Bowman, BA
中科院分区：
文献类型：
--
作者：
Nesby-O'Dell, S;Scanlon, KS;Bowman, BA
背景：最近关于非裔美国儿童软骨病的报道引起了人们对这些婴儿及其母亲维生素D状况的关注。非裔美国女性比白人女性维生素D缺乏的风险更高，但很少有研究研究这一人群中维生素D缺乏症的决定因素。目的：我们调查了非洲裔美国女性和育龄白人女性中维生素D缺乏症的患病率和决定因素。设计：我们调查了1546名非洲裔美国女性和1426名15-49岁未怀孕的白人女性，她们参加了第三次全国健康和营养调查(1988-1994)。维生素D缺乏症定义为血清25-羟基维生素D浓度小于或等于37.5nmol/L。采用多元Logistic回归分析饮食、人口学和行为因素与维生素D缺乏症的独立关联。结果：非裔美国人和白人的维生素D缺乏症患病率分别为42.4+/-3.1%和4.2+/-0.7%。在非裔美国人中，维生素D缺乏症与每周3次牛奶或早餐谷类食品的消费、不使用维生素D补充剂、季节、城市居住、低体重指数和不使用口服避孕药独立相关。即使在从补充剂中摄入足够维生素D的243名非裔美国人中，也有28.2+/-2.7%的人患有维生素D缺乏症。结论：非裔美国女性维生素D缺乏症的高患病率值得进一步研究这些女性的维生素D推荐。当建议妇女饮食摄入和补充剂使用时，应考虑妇女维生素D缺乏症的决定因素。
Background: Recent reports of rickets among African American children drew attention to the vitamin D status of these infants and their mothers. African American women are at higher risk of vitamin D deficiency than are white women, but few studies have examined determinants of hypovitaminosis D in this population.Objective: We examined the prevalence and determinants of hypovitaminosis D among African American and white women of reproductive age.Design: We examined 1546 African American women and 1426 white women aged 15-49 y who were not pregnant and who participated in the third National Health and Nutrition Examination Survey (1988-1994). Hypovitaminosis D was defined as a serum 25-hydroxyvitamin D concentration less than or equal to 37.5 nmol/L. Multiple logistic regression was used to examine the independent association of dietary, demographic, and behavioral determinants of hypovitaminosis D.Results: The prevalence of hypovitaminosis D was 42.4 +/- 3.1% (T SE) among African Americans and 4.2 +/- 0.7% among whites. Among African Americans, hypovitaminosis D was independently associated with consumption of milk or breakfast cereal < 3 times/wk, no use of vitamin D supplements, season, urban residence, low body mass index, and no use of oral contraceptives. Even among 243 African Americans who consumed the adequate intake of vitamin D from supplements , 28.2 +/- 2.7% had hypovitaminosis D.Conclusions: The high prevalence of hypovitaminosis D among African American women warrants further examination of vitamin D recommendations for these women. The determinants of hypovitaminosis D among women should be considered when these women are advised on dietary intake and supplement use.