Dynamic reflectometer for control of laser photocoagulation on the retina.
Dynamic reflectometer for control of laser photocoagulation on the retina.
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用于控制视网膜激光光凝的动态反射计。
DOI：
10.1002/lsm.1900150108
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发表时间：
1994
影响因子：
2.4
通讯作者：
Birngruber,R
中科院分区：
文献类型：
--
作者：
Inderfurth,JH;Ferguson,RD;Frish,MB;Birngruber,R
在视网膜激光光凝术中，恒定的曝光参数不会导致相同的病变。这种重复性的缺乏增加了过度治疗或治疗不足引起的并发症的发生率，并阻碍了不同视网膜疾病最佳治疗终点的确定。为此，反馈控制的光凝器可以使视网膜光凝变得更安全、更具重复性和更快的过程。将动态共焦反射计集成到裂隙灯激光传输系统中。通过监测氩激光光凝过程中凝固光束背向散射光的增加，获得了色素兔视网膜的实时反射率变化。测量了可重复的时间反射率模式，该模式与检眼镜评估的病变强度相关，与曝光参数、光学介质的透明度和聚焦条件无关。作为反馈控制光凝器开发的一个步骤，共焦反射计已在动物试验中得到证明，与临床实践非常相似。 © 1994 Wiley-Liss, Inc.
In retinal laser photocoagulation, constant exposure parameters do not result in identical lesions. This lack of reproducibility increases the rate of complications from over‐or undertreatment and inhibits determination of the optimal treatment endpoints for different retinal disorders. To this end, a feedback‐controlled photocoagulator could make retinal photocoagulation a safer, more reproducible, and faster procedure. A dynamic confocal reflectometer was integrated into a slit lamp laser delivery system. Real‐time reflectance changes on the retinas of pigmented rabbits were obtained by monitoring the increasing back‐scattered light of the coagulating beam during argon laser photocoagulation. Reproducible temporal reflectance patterns were measured that correlated with ophthalmoscopically assessed lesion intensity independent of the exposure parameters, the transparency of the optical media, and the focusing conditions. As a step toward the development of a feedback‐controlled photocoagulator, the confocal reflectometer has been proven in animal trials closely resembling clinical practice. © 1994 Wiley‐Liss, Inc.