Organochlorine compounds and concentrations of thyroid stimulating hormone in newborns
Organochlorine compounds and concentrations of thyroid stimulating hormone in newborns
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DOI：
10.1136/oem.60.4.301
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发表时间：
2003-04-01
影响因子：
4.9
通讯作者：
Sunyer, J
中科院分区：
文献类型：
--
作者：
Ribas-Fitó, N;Sala, M;Sunyer, J
目的：探讨六氯苯(HCB)污染高发区新生儿出生前有机氯暴露与甲状腺状况的关系。方法：收集1997~1999年出生在六氯苯污染地区的98对母婴(占出生儿童总数的83.1%)。检测了70份脐带血标本中有机氯化合物的含量。结果：所有新生儿TSH水平均在正常参考值范围内(P<0.05)。
Aims: To assess the association between prenatal exposure to organochlorine compounds and thyroid status in newborns from an area with high levels of hexachlorobenzene (HCB).Methods: A total of 98 mother-infant pairs (83.1% of all children born during the period 1997-99 in a specific area polluted with HCB) were recruited. Levels of organochlorine compounds were measured in 70 cord serum samples. Concentrations of thyroid stimulating hormone (TSH) were measured in plasma of all newborns three days after birth.Results: All newborns had concentrations of TSH within the range of normal reference values (