Non-reciprocal control of rhythmic activity in respiratory-modulated XII motoneurons.
Non-reciprocal control of rhythmic activity in respiratory-modulated XII motoneurons.
复制标题
呼吸调节 XII 运动神经元节律活动的非交互控制。
DOI：
10.1097/00001756-199510010-00031
复制
发表时间：
1995
期刊：
影响因子：
1.7
通讯作者：
Kubin,L
中科院分区：
文献类型：
--
作者：
Woch,G;Kubin,L
为了阐明舌下神经（XII）运动神经元的阶段性呼吸输入的性质，我们评估了吸气和呼气调制的运动神经元的膜电阻（RN）的阶段性变化。在呼气运动神经元中，R N在吸气时始终低于呼气时，并且细胞内注射负电流逆转了吸气时的相性超极化膜电位波。在吸气运动神经元中，R N变化较小，但在吸气时也是最小的。在这些神经元中，注射足以逆转舌神经诱发的IPSP的负电流并不能逆转相性呼气超极化。因此，呼吸相关的抑制性输入是非互惠的吸气和呼气XII运动神经元，与吸气运动神经元可能缺乏体细胞，氨基酸介导的抑制性输入呼气。
To elucidate the nature of phasic respiratory inputs to hypoglossal (XII) motoneurons, we assessed the phasic changes in membrane resistance (R N) in inspiratory-and expiratory-modulated motoneurons. In expiratory motoneurons, R N was consistently lower in inspiration than in expiration and intracellular injection of negative current reversed the phasic hyperpolarizing membrane potential wave in inspiration. In inspiratory motoneurons, R N changed less but also was minimal in inspiration. In these neurons, injection of a negative current sufficient to reverse a lingual nerve-evoked IPSP did not reverse the phasic expiratory hyperpolarization. Thus, respiratory-related inhibitory inputs are non-reciprocal in inspiratory and expiratory XII motoneurons, with inspiratory motoneurons probably lacking a somatic, amino acid-mediated inhibitory input in expiration.