ParaAT: A parallel tool for constructing multiple protein-coding DNA alignments
ParaAT: A parallel tool for constructing multiple protein-coding DNA alignments
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DOI：
10.1016/j.bbrc.2012.02.101
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发表时间：
2012-03-23
影响因子：
3.1
通讯作者：
Dai，Lin
中科院分区：
文献类型：
--
作者：
Zhang，Zhang;Xiao，Jingfa;Dai，Lin
Constructing multiple homologous alignments for protein-coding DNA sequences is crucial for a variety of bioinformatic analyses but remains computationally challenging. With the growing amount of sequence data available and the ongoing efforts largely dependent on protein-coding DNA alignments, there is an increasing demand for a tool that can process a large number of homologous groups and generate multiple protein-coding DNA alignments. Here we present a parallel tool – ParaAT that is capable of parallelly constructing multiple protein-coding DNA alignments for a large number of homologs. As testified on empirical datasets, ParaAT is well suited for large-scale data analysis in the high-throughput era, providing good scalability and exhibiting high parallel efficiency for computationally demanding tasks. ParaAT is freely available for academic use only at http://cbb.big.ac.cn/software.
