Prognostic significance and dynamic change of plasma macrophage migration inhibitory factor in patients with acute ST-elevation myocardial infarction.

Prognostic significance and dynamic change of plasma macrophage migration inhibitory factor in patients with acute ST-elevation myocardial infarction.
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急性ST段抬高型心肌梗死患者血浆巨噬细胞迁移抑制因子的预后意义及动态变化

DOI:
10.1097/md.0000000000012991
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发表时间:
2018-10
期刊:
影响因子:
1.6
通讯作者:
Zhou J
Zhou J
中科院分区:
医学4区
文献类型:
--
作者:
Deng F;Zhao Q;Deng Y;Wu Y;Zhou D;Liu W;Yuan Z;Zhou J

文献摘要

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Macrophage migration inhibitory factor (MIF) has been reported as an inflammatory cytokine in many inflammatory diseases, including rheumatoid arthritis and ischemic diseases. However, dynamic changes of MIF within the first 24 hours on admission and potential prognostic significance following ST-elevation myocardial infarction (STEMI) have been little known. In this study, we examined the dynamic change of MIF level and its potential diagnostic and prognostic value after the onset of STEMI. Plasma MIF levels were evaluated in symptomatic subjects who received coronary angiogram with a median 27 months follow-up for the development of major adverse cardiovascular events (MACEs).