Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices.
Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices.
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DOI：
10.1039/b924816a
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发表时间：
2010-03-07
期刊：
影响因子：
6.1
通讯作者：
Zahn JD
中科院分区：
文献类型：
--
作者：
Aran K;Sasso LA;Kamdar N;Zahn JD
描述了一种将聚碳酸酯、聚醚砜和聚对苯二甲酸乙二醇酯等多孔聚合物膜集成到微流控装置中的方法。扩展了3-氨基丙基三乙氧基硅烷作为化学交联剂的使用，使膜与PDMS和玻璃微流控通道相结合。在膜和微流控结构之间形成了一种强而不可逆的结合。APTES处理的器件的结合强度明显高于使用PDMS“胶”或两组分环氧树脂粘合方法制造的器件。通过扫描电镜对过滤微装置和孔结构的评价表明，APTES偶联不会显著改变膜的运输功能和孔形态。
A method for integrating porous polymer membranes such as polycarbonate, polyethersulfone and polyethylene terephthalate to microfluidic devices is described. The use of 3-amino-propyltriethoxysilane as a chemical crosslinking agent was extended to integrate membranes with PDMS and glass microfluidic channels. A strong, irreversible bond between the membranes and microfluidic structure was achieved. The bonding strength in the APTES treated devices was significantly greater than in devices fabricated using either a PDMS “glue” or two-part epoxy bonding method. Evaluation of a filtering microdevice and the pore structure via SEM indicates the APTES conjugation does not significantly alter the membrane transport function and pore morphology.