Quality of life and cancer-related needs in patients with choroidal melanoma.
Quality of life and cancer-related needs in patients with choroidal melanoma.
复制标题
脉络膜黑色素瘤患者的生活质量和癌症相关需求。
DOI：
10.1136/bjophthalmol-2013-303635
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Stanton,AnnetteL
中科院分区：
文献类型：
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作者：
Wiley,JoshuaF;Laird,Kelsey;Beran,Tammy;McCannel,TaraA;Stanton,AnnetteL
AimsTo assess quality of life (QoL) indices and their associations with treatment modality, sociodemographics and cancer-related needs in choroidal melanoma patients.MethodsPatients (N=99) treated at the University of California, Los Angeles, for choroidal melanoma within the prior 5 years (M=2.05) completed questionnaires assessing demographics, cancer-related needs, vision-specific QoL, depressive symptoms and concern about recurrence. Visual acuity, comorbidities, treatment modality (radiotherapy, enucleation) and years since diagnosis were gathered from medical records. Primary analyses were multiple regressions.ResultsAlthough concern about cancer recurrence was elevated, QoL was better than in other oncology samples and comparable with healthy samples on some outcomes. Enucleation was associated with worse vision-specific QoL, and presence of comorbid diseases was associated with worse vision-specific QoL, depressive symptoms and concern about cancer recurring (all p values<0.05). Patients who experienced at least one stressful life event in the past year (vs no events) reported more depressive symptoms (p<0.01). Report of more unmet cancer needs was associated with worse vision-specific QoL, depressive symptoms and more concern about recurrence (all p values<0.05), uniquely explaining 4%–12% of the variance.ConclusionsFor choroidal melanoma patients, an average of 2 years after treatment, the number of physical comorbidities and unmet cancer needs were the strongest correlates of poorer QoL.
