Reinvestigation of the Absolute Stereochemistry of Megastigmane Glucoside, Icariside B5
Reinvestigation of the Absolute Stereochemistry of Megastigmane Glucoside, Icariside B5
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DOI：
10.1248/cpb.58.1399
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发表时间：
2010-10-01
影响因子：
1.7
通讯作者：
Miyase, Toshio
中科院分区：
文献类型：
--
作者：
Matsunami, Katsuyoshi;Otsuka, Hideaki;Miyase, Toshio
Icariside B-5是一种广泛分布于植物源的大藤甲苷。应用改进的Mosher法，通过相关化合物的化学转化，重新研究了icariside B-5的绝对结构。结果表明，icariside B-5的结构为(6S,9S)-6,9-dihydroxymegastigman-4-en-3-one 9- o - β -d -glucopyranoside。
Icariside B-5 is one of the widely distributed megastigmane glucosides among plant sources. The absolute structure of icariside B-5 was reinvestigated by chemical conversion from the related compound and the application of the modified Mosher's method. As a result, the structure of icariside B-5 was revised to be (6S,9S)-6,9-dihydroxymegastigman-4-en-3-one 9-O-beta-D-glucopyranoside.