Antimicrobial resistance preparedness in sub-Saharan African countries
Antimicrobial resistance preparedness in sub-Saharan African countries
复制标题
DOI：
10.1186/s13756-020-00800-y
复制
发表时间：
2020-08-28
影响因子：
5.5
通讯作者：
McHugh, Timothy D.
中科院分区：
文献类型：
--
作者：
Elton, Linzy;Thomason, Margaret J.;McHugh, Timothy D.
抗微生物药物耐药性（AMR）是全球日益关注的问题，由于缺乏实时数据记录、监测和监管，撒哈拉以南非洲（SSA）的AMR状况尚不明确。世界卫生组织（世卫组织）联合外部评价（JEE）报告是自愿的协作过程，用于评估国家预防、发现和快速应对包括抗菌素耐药性在内的公共卫生风险的能力和准备情况。对SSA JEE报告中的数据进行了分析，以概述SSA如何开展抗微生物药物耐药性准备工作以及优势和劣势所在。方法对SSA国家JEE AMR防范评分进行分析。计算所有SSA国家抗菌素耐药性准备得分的累积平均值，并与SSA JEE总体平均得分进行比较。对抗菌素耐药性防范指标进行了分析，并按区域对数据进行加权。发现SSA AMR准备的平均得分比SSA JEE的总体平均得分低53%。东非报告制定了抗微生物药物耐药性国家行动计划以及制定了人类和动物病原体抗微生物药物耐药性监测规划的国家比例最高。南部非洲拥有培训规划和抗微生物药物管理的国家比例最高。与JEE总体得分相比，抗菌素耐药性的平均准备得分较低，而且大多数国家缺乏实施的国家行动计划，这表明到目前为止，抗菌素耐药性还不是大多数SSA国家的优先事项。通过确定区域和“同一个健康”的优势，可以通过多部门方法加强整个SSA的抗菌素耐药性防范工作。
Background Antimicrobial resistance (AMR) is of growing concern globally and AMR status in sub-Saharan Africa (SSA) is undefined due to a lack of real-time data recording, surveillance and regulation. World Health Organization (WHO) Joint External Evaluation (JEE) reports are voluntary, collaborative processes to assess country capacities and preparedness to prevent, detect and rapidly respond to public health risks, including AMR. The data from SSA JEE reports were analysed to gain an overview of how SSA is working towards AMR preparedness and where strengths and weaknesses lie. Methods SSA country JEE AMR preparedness scores were analysed. A cumulative mean of all the SSA country AMR preparedness scores was calculated and compared to the overall mean SSA JEE score. AMR preparedness indicators were analysed, and data were weighted by region. Findings The mean SSA AMR preparedness score was 53% less than the overall mean SSA JEE score. East Africa had the highest percentage of countries reporting having AMR National Action Plans in place, as well as human and animal pathogen AMR surveillance programmes. Southern Africa reported the highest percentage of countries with training programmes and antimicrobial stewardship. Conclusions The low mean AMR preparedness score compared to overall JEE score, along with the majority of countries lacking implemented National Action Plans, suggests that until now AMR has not been a priority for most SSA countries. By identifying regional and One Health strengths, AMR preparedness can be fortified across SSA with a multisectoral approach.