LYMPH-NODE METASTASIS FROM EARLY GASTRIC-CANCER - ENDOSCOPIC RESECTION OF TUMOR

LYMPH-NODE METASTASIS FROM EARLY GASTRIC-CANCER - ENDOSCOPIC RESECTION OF TUMOR
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DOI:
10.1002/bjs.1800790319
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发表时间:
1992-03-01
影响因子:
9.6
通讯作者:
MUTO, T
MUTO, T
中科院分区:
医学1区
文献类型:
--
作者:
SANO, T;KOBORI, O;MUTO, T

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本文对748例孤立性早期胃癌的临床病理特征及淋巴结转移进行了分析。在几个因素中,只有浸润深度和肿瘤大小与淋巴结累及有显著相关性。满足以下条件的肿瘤可能不会转移到淋巴结:(1)局限于粘膜;(二)直径小于1.5厘米的;(3)宏观提升;(4)宏观上抑郁,无胃溃疡或溃疡疤痕(内窥镜下,无褶皱收敛);(5)组织学分化。随着最近发展的内镜技术,小胃肿瘤可以安全地切除。肿瘤侵袭的切缘和深度可以在标本中得到组织学证实。如果内镜切除的肿瘤满足上述标准,则可以选择进一步的手术干预,因为内镜切除的结果与没有累及淋巴结的根治性手术的结果相当。
The clinicopathological features of 748 solitary early gastric cancers were examined with regard to lymph node metastasis. Among several factors, only depth of invasion and tumour size correlated significantly with node involvement. Tumours which satisfy the following criteria may not metastasize to lymph nodes: (1) confined to the mucosa; (2) less than 1.5 cm in diameter; (3) macroscopically elevated; (4) macroscopically depressed, without intramural ulcers or ulcer scars (endoscopically, no fold convergence); and (5) histologically differentiated. With a recently developed endoscopic technique small gastric tumours can safely be resected. The cut margin and depth of tumour invasion can be verified histologically in the specimen. If an endoscopically removed tumour satisfies the above criteria, further surgical intervention may be optional as the outcome of endoscopic resection is comparable to that of radical surgery in the absence of node involvement.