THE TOTAL SYNTHESIS OF (+)-RYANODOL .3. PREPARATION OF (+)-ANHYDRORYANODOL FROM A KEY PENTACYCLIC INTERMEDIATE
THE TOTAL SYNTHESIS OF (+)-RYANODOL .3. PREPARATION OF (+)-ANHYDRORYANODOL FROM A KEY PENTACYCLIC INTERMEDIATE
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DOI：
10.1139/v90-023
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发表时间：
1990-01-01
影响因子：
1.1
通讯作者：
SOUCY, P
中科院分区：
文献类型：
--
作者：
DESLONGCHAMPS, P;BELANGER, A;SOUCY, P
本文报道了为了解如何将右旋五环关键中间体5转化为（+）-脱水谷草醇（6）而进行的几项研究。该转化需要24个步骤，并通过以下中间体进行：5 →11. →[19] 34. 36. 39. 144. 150. 6.关键的五环中间体5的制备在本系列的第一部分和第二部分中报道。
This paper reports several studies that were carried out to learn how to transform the dextrororatory pentacyclic key intermediate 5 into (+)-anhydroryanodol (6). This transformation requires 24 steps, and takes place via the following intermediates: 5 .fwdarw. 11 .fwdarw. 19 .fwdarw. 34 .fwdarw. 36 .fwdarw. 39 .fwdarw. 144 .fwdarw. 150 .fwdarw. 6. The preparation of the key pentacyclic intermediate 5 is reported in Parts I and II of this series.