Clinical usefulness of the two-question assessment tool for depressive symptoms in Japanese patients with chronic obstructive pulmonary disease.
Clinical usefulness of the two-question assessment tool for depressive symptoms in Japanese patients with chronic obstructive pulmonary disease.
复制标题
两问题评估工具对日本慢性阻塞性肺病患者抑郁症状的临床实用性。
DOI：
10.1007/s00408-012-9437-1
复制
发表时间：
2013
期刊：
影响因子：
5
通讯作者：
Nakazato M.
中科院分区：
文献类型：
--
作者：
Arimura Y;Yamazaki S;Yanagi S;Matsumoto N;Takegami M;Hayashino Y;Fukuhara S;Nakazato M.
目的抑郁症状在慢性阻塞性肺疾病(COPD)患者中非常普遍，且与不良预后相关。在门诊环境中，需要开发一份简明的问卷来衡量COPD患者的抑郁症状。我们评估了一种简明的两个问题的工具评估慢性阻塞性肺疾病患者抑郁症状的临床有效性。所有患者都完成了一份自我报告问卷，其中包括两个问题的工具，以及衡量抑郁症状的流行病研究中心抑郁量表(CESD-10)的简化版本。以CESD-10的测评结果为标准，对两题测验的性能进行了评价。结果两题量表检测抑郁症状的灵敏度为73.3%(95%可信区间51~95.7)，特异度为73.3%(95%可信区间58.7~87.3)，受试者工作特征曲线下面积为0.73(95%可信区间0.59~0.87)。当研究对象被分成两组，两题总分为1分时，有抑郁症状的患者在SF-8中除“躯体疼痛”外的所有分量表的得分均显著低于无抑郁症状的患者。结论该简明的两问题问卷可用于评估繁忙的门诊COPD患者的抑郁症状。
PurposeDepressive symptoms are highly prevalent in patients with chronic obstructive pulmonary disease (COPD) and have been associated with poor outcomes. Developing a concise questionnaire to measure depressive symptoms in COPD patients is needed in outpatient settings. We evaluated the clinical usefulness of a concise two-question instrument to assess depressive symptoms in patients with COPD.MethodsThe study was conducted as a cross-sectional analysis in patients with COPD. All patients completed a self-reported questionnaire consisting of the two-question instrument, as well as a shortened version of the Center for Epidemiologic Studies Depression Scale (CESD-10) to measure depressive symptoms. Performance of the two-question instrument was evaluated using the results for CESD-10 as standard. We also measured patients’ health-related quality of life using the Medical Outcomes Study 8-Item Short-Form Health Survey (SF-8) to determine whether the instrument was related to SF-8.ResultsSensitivity of the two-question instrument in the detection of depressive symptoms was 73.3 % (95 % confidence interval [CI] 51–95.7), specificity was 73 % (95 % CI 58.7–87.3), and area under the receiver operating characteristics curve was 0.73 (95 % CI 0.59–0.87). When study patients were divided into two groups with a cutoff of 1 point on the two-question instrument, scores for all subscales of the SF-8 except “bodily pain” were significantly lower in patients with than without depressive symptoms.ConclusionsThis concise two-question instrument is useful as assessment of depressive symptom in patients with COPD in busy outpatient settings.