Neural progenitors and stem cells: mechanisms of progenitor heterogeneity
Neural progenitors and stem cells: mechanisms of progenitor heterogeneity
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DOI：
10.1016/s0959-4388(98)80006-8
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发表时间：
1998-02
影响因子：
5.7
通讯作者：
L. Lillien
中科院分区：
文献类型：
--
作者：
L. Lillien
在过去的几年里，脊椎动物神经系统中祖细胞之间的异质性已经被越来越多的报道。很明显，祖细胞的差异有助于确定它们何时以及如何对环境信号做出反应。最近的研究已经开始阐明祖细胞亚群差异的分子基础，这些亚群控制其发育潜力和对环境信号的反应。
Heterogeneity among progenitor cells in the vertebrate nervous system has been documented with increasing frequency over the past few years. It has become clear that differences in progenitor cells help to determine when and how they respond to environmental signals. More recent studies have begun to elucidate the molecular basis of the differences in progenitor cell subpopulations that control their developmental potential and responsiveness to environmental signals.