Marijuana Use Among Young Black Men Who Have Sex With Men and the HIV Care Continuum: Findings From the uConnect Cohort.

Marijuana Use Among Young Black Men Who Have Sex With Men and the HIV Care Continuum: Findings From the uConnect Cohort.
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DOI:
10.1080/10826084.2016.1197265
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发表时间:
2016-11-09
影响因子:
2
通讯作者:
Schneider JA
Schneider JA
中科院分区:
医学4区
文献类型:
--
作者:
Morgan E;Khanna AS;Skaathun B;Michaels S;Young L;Duvoisin R;Chang M;Voisin D;Cornwell B;Coombs RW;Friedman SR;Schneider JA

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在美国,与男性发生性关系的年轻黑人男性(YBMSM)是艾滋病毒血清转化的最高风险。艾滋病毒护理连续体的成功运作是限制艾滋病毒传播的重要干预措施。关于YBMSM最常用的物质(如大麻)与HIV连续体的关系,几乎没有数据,这是本研究的主要目的。YBMSM(N=618)的队列,通过响应驱动抽样产生。使用加权逻辑回归模型评估了整个艾滋病毒护理连续体中大麻使用和大麻作为性药物使用的频率。研究参与者报告了更多的间歇性大麻使用(n=254,56.2%)相比,大量使用(n=198,43.8%)。我们的样本包含212(34.3%)HIV血清阳性的参与者,其中52(24.5%)不知道他们的HIV阳性状态。重度大麻使用者的研究参与者更有可能不知道他们的HIV血清阳性状态(AOR:4.18; 95% CI 1.26,13.89)。护理连续体中的所有其他阶段都表明,间歇性或大量使用大麻或作为性药物的人与非使用者之间没有显着差异。与大量吸食大麻的男性发生性关系的年轻黑人男性比那些从未吸食大麻的男性更有可能在不知情的情况下感染艾滋病毒。关于大麻使用和其他艾滋病毒护理连续体指标之间的关系,调查结果是不确定的。然而,了解自己的艾滋病毒状况是从事护理的一个关键要求,并可能对艾滋病毒的传播产生影响。
Young Black men who have sex with men (YBMSM) are at highest risk for HIV seroconversion in the United States. Successful movement through the HIV care continuum is an important intervention for limiting onwards HIV transmission. Little data exists on how substances most commonly used by YBMSM, such as marijuana, are related to the HIV continuum, which represents the primary aim of this study. A cohort of YBMSM (N=618) was generated through respondent-driven sampling. Frequency of marijuana use and marijuana use as a sex drug were assessed across the HIV care continuum using weighted logistic regression models. Study participants reported more intermittent marijuana use (n=254, 56.2%) compared to heavy use (n=198, 43.8%). Our sample contained 212 (34.3%) HIV seropositive participants of which 52 (24.5%) were unaware of their HIV positive status. Study participants who were heavy marijuana users were more likely to be unaware of their HIV seropositive status (AOR: 4.18; 95% CI 1.26, 13.89). All other stages in the care continuum demonstrated no significant differences between those who use marijuana intermittently or heavily or as a sex-drug and non-users. Young Black men who have sex with men who used marijuana heavily were more likely to be HIV-positive unaware than those who never used marijuana. Findings were inconclusive regarding the relationships between marijuana use and other HIV care continuum metrics. However, knowledge of ones' HIV status is a critical requirement for engaging in care and may have implications for onwards HIV transmission.
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