Dissociating Source Memory Decisions in the Prefrontal Cortex: fMRI of Diagnostic and Disqualifying Monitoring
Dissociating Source Memory Decisions in the Prefrontal Cortex: fMRI of Diagnostic and Disqualifying Monitoring
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DOI：
10.1162/jocn.2009.21263
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发表时间：
2010-05-01
影响因子：
3.2
通讯作者：
Scimeca, Jason
中科院分区：
文献类型：
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作者：
Gallo, David A.;McDonough, Ian M.;Scimeca, Jason
我们使用事件相关功能磁共振成像研究了两种调节情景记忆准确性的检索监测：诊断监测和取消资格监测。诊断监控依赖于期望，因此无法检索期望的回忆可以防止源记忆错误归因（有时称为独特性启发式）。取消资格监测依赖于确凿的证据，因此，成功地回忆准确的来源信息可以防止错误地归因于另一个来源（有时称为回忆拒绝）。通过标准回忆测试，我们发现与对照测试相比，面向显著性记忆（彩色图片）的检索减少了源记忆错误归因。然而，相应的神经活动取决于参与这些测试的监测类型。与对照测试相比，拒绝基于图片回忆缺失的项目（即，独特性启发式）降低了背外侧前额叶皮层的活动，而拒绝基于成功的图片回忆的项目（即，回忆-拒绝策略）增加了背外侧前额叶皮层的活动。还有一些证据表明，这些影响是不同侧面的。本研究首次对这两种基于回忆的监测过程进行了神经影像学比较，并提出了前额叶参与记忆提取的理论。
We used event-related fMRI to study two types of retrieval monitoring that regulate episodic memory accuracy: diagnostic and disqualifying monitoring. Diagnostic monitoring relies on expectations, whereby the failure to retrieve expected recollections prevents source memory misattributions (sometimes called the distinctiveness heuristic). Disqualifying monitoring relies on corroborative evidence, whereby the successful recollection of accurate source information prevents misattribution to an alternative source (sometimes called recall to reject). Using criterial recollection tests, we found that orienting retrieval toward distinctive recollections (colored pictures) reduced source memory misattributions compared with a control test in which retrieval was oriented toward less distinctive recollections (colored font). However, the corresponding neural activity depended on the type of monitoring engaged on these tests. Rejecting items based on the absence of picture recollections (i.e., the distinctiveness heuristic) decreased activity in dorsolateral prefrontal cortex relative to the control test, whereas rejecting items based on successful picture recollections (i.e., a recall-to-reject strategy) increased activity in dorsolateral prefrontal cortex. There also was some evidence that these effects were differentially lateralized. This study provides the first neuroimaging comparison of these two recollection-based monitoring processes and advances theories of prefrontal involvement inmemory retrieval.