Cardiac autonomic functioning and post-traumatic stress: A preliminary study in youth at-risk for PTSD
Cardiac autonomic functioning and post-traumatic stress: A preliminary study in youth at-risk for PTSD
复制标题
DOI：
10.1016/j.psychres.2019.112684
复制
发表时间：
2020-02-01
影响因子：
11.3
通讯作者：
Menon, Suvarna, V
中科院分区：
文献类型：
--
作者：
Cohen, Joseph R.;Thomsen, Kari N.;Menon, Suvarna, V
确定与创伤有关的痛苦的强大的心理生理标志物对于为青年制定全面的、了解创伤的心理健康评估至关重要。因此，本研究探讨了心脏自主神经平衡（CAB）和心脏自主神经调节（CAR），交感神经和副交感神经系统的两个复合指标的临床效用。我们假设CAB/CAR与测量副交感神经（即，呼吸性窦性心律不齐; RSA）和交感神经（即，射血前期; PEP）神经系统隔离。我们的样本由88名不同的低收入青年组成（40.9%为非洲裔美国人，36.4%为白色; 60.5%为女孩; M年龄= 12.05岁; SD年龄= 1.57），这些青年的不良暴露风险增加。在5分钟的基线期和5分钟的亲子冲突讨论任务中测量RSA和PEP。青少年照顾者二人组完成了一个临床医生管理的措施，青年的一生创伤暴露和目前的PTS。CAB代表RSA和PEP之间的差值，而CAR是RSA和PEP的总和。分析表明，交感神经导向的CA B反应性独特地（a）索引PTS，特别是在升高的创伤的背景下，和（B）区分那些与非PTSD。研究结果强调了使用生理标记的翻译承诺，占副交感神经和交感神经系统之间的平衡。
The identification of robust, psychophysiological markers of trauma-related distress is critical for developing comprehensive, trauma-informed, mental health assessments for youth. Thus, the present study examined the clinical utility of cardiac autonomic balance (CAB) and cardiac autonomic regulation (CAR), two composite indices of the sympathetic and parasympathetic nervous system. We hypothesized that CAB/CAR would more reliably index post-traumatic stress (PTS) responses compared to measuring the parasympathetic (i.e., respiratory sinus arrhythmia; RSA) and sympathetic (i.e., pre-ejection period; PEP) nervous systems in isolation. Our sample was comprised of 88 diverse, low-income youth (40.9% African-American and 36.4% White; 60.5% girls; M-age = 12.05 years; SDage = 1.57) who are at increased risk for adversity-exposure. RSA and PEP were measured during a 5-minute baseline period and 5-minute parent-child conflict discussion task. Adolescent-caregiver dyads completed a clinician-administered measure of the youth's lifetime trauma-exposure and current PTS. CAB represented the difference between RSA and PEP, while CAR was the summation of RSA and PEP. Analyses revealed that sympathetically-oriented CAB reactivity uniquely (a) indexed PTS, especially in the context of elevated trauma, and (b) distinguished between those with and without PTSD. Findings highlight the translational promise of using physiological markers that account for the balance between the parasympathetic and sympathetic nervous system.