Hepatic sinusoidal obstruction syndrome in patients undergoing hematopoietic stem cell transplant.

Hepatic sinusoidal obstruction syndrome in patients undergoing hematopoietic stem cell transplant.
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接受造血干细胞移植患者的肝窦阻塞综合征。

DOI:
10.1188/08.onf.385-397
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发表时间:
2008
影响因子:
1.9
通讯作者:
S. Eisenberg
S. Eisenberg
中科院分区:
医学4区
文献类型:
--
作者:
S. Eisenberg

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目的/目标 旨在对接受造血干细胞移植的患者的肝窦阻塞综合征 (HSOS) 进行全面回顾,并描述其对护理的影响。 数据来源 发表研究文章、评论、案例报告和书籍。 数据综合 关于 HSOS 的确切原因存在分歧。预防和治疗策略是基于这些致病理论而出现的。尽管可以成功使用源自其他疾病病因的症状管理策略,但可用于针对 HSOS 的护理评估和干预的已发表资源很少。 结论 HSOS 是清髓性放化疗的复杂后果。尽管总体发病率正在下降,但研究仍在继续探索更好的预防方法并开发更有效的治疗方案。 对护理的影响 护理接受造血干细胞移植的患者的护士必须了解 HSOS 的病因并熟悉该综合征的表现。症状管理需要对受影响的器官系统有透彻的了解。
PURPOSE/OBJECTIVES To provide a comprehensive review of hepatic sinusoidal obstruction syndrome (HSOS) in patients receiving a hematopoietic stem cell transplant and to describe the implications for nursing care. DATA SOURCES Published research articles, reviews, case reports, and books. DATA SYNTHESIS Disagreement exists regarding the precise cause of HSOS. Prevention and treatment strategies have emerged based on these causative theories. Few published resources are available for nursing assessment and intervention specific to HSOS, although symptom management strategies derived from other disease etiologies can be used successfully. CONCLUSIONS HSOS is a complex consequence of myeloablative chemoradiotherapy. Although the overall incidence is declining, research continues to explore better methods for prophylaxis and develop more efficacious treatment options. IMPLICATIONS FOR NURSING Nurses caring for patients receiving a hematopoietic stem cell transplant must comprehend the proposed etiologies for HSOS and be familiar with the manifestations of the syndrome. Symptom management requires a thorough understanding of affected organ systems.
DOI: 10.1182/blood-2005-07-2681
发表时间: 2006-01-01
期刊: BLOOD
影响因子: 20.3
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Smith, LH;Dixon, JD;Vaughan, DE
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期刊: BLOOD
影响因子: 20.3
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DOI: 10.1016/s1083-8791(99)70006-6
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期刊: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
影响因子: --
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期刊: Blood
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DOI: 10.1016/j.beha.2005.11.008
发表时间: 2006
期刊: Best practice & research. Clinical haematology
影响因子: --
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通讯作者: McDonald,GeorgeB