What goes up must come down
What goes up must come down
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DOI：
10.1038/8969
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发表时间：
1999-05-01
影响因子：
21.3
通讯作者：
Leevers, SJ
中科院分区：
文献类型：
--
作者：
Leevers, SJ
在果蝇发育过程中，表皮生长因子受体的活性受到高度调控。涉及Kekkon1和Sprouty蛋白的两个负反馈环被发现通过完全不同的抑制机制发挥作用。
The activity of the epidermal-growth-factor receptor is highly regulated during Drosophila development. Two negative-feedback loops involving the proteins Kekkon1 and Sprouty have been found to act by quite different inhibitory mechanisms.