Effect of variable power levels on the yield of total aerosol mass and formation of aldehydes in e-cigarette aerosols

Effect of variable power levels on the yield of total aerosol mass and formation of aldehydes in e-cigarette aerosols
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DOI:
10.1016/j.yrtph.2015.12.019
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发表时间:
2016-03-01
影响因子:
3.4
通讯作者:
Paolantonio, A. R.
Paolantonio, A. R.
中科院分区:
医学3区
文献类型:
--
作者:
Gillman, I. G.;Kistler, K. A.;Paolantonio, A. R.

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研究目的是确定应用于基于可再填充罐的电子烟(EC)装置的雾化器的可变功率的效果。对5种不同器械进行了评价,每种器械有4个功率水平。对于每组25次EC抽吸,气溶胶产率结果报告为质量/抽吸,并且针对施加到线圈的功率进行归一化,以质量/瓦特计。每次抽吸产生的气溶胶的范围为1.5至28 mg,并且对于施加到线圈的功率进行归一化,范围为0.27至1.1 mg/W。还分析了气溶胶样品中甲醛,乙醛和丙烯醛的生产,作为DNPH衍生物,在每个功率水平。当以质量为基础报告时,其中三个装置显示出总醛产率随着施加到线圈的功率的增加而增加,而其中两个装置显示出相反的趋势。每克产生的总气溶胶产生的甲醛、乙醛和丙烯醛的质量范围为0.01至73 mg/g、0.006至5.8 mg/g和0.008至5.8 mg/g。
The study objective was to determine the effect of variable power applied to the atomizer of refillable tank based e-cigarette (EC) devices. Five different devices were evaluated, each at four power levels. Aerosol yield results are reported for each set of 25 EC puffs, as mass/puff, and normalized for the power applied to the coil, in mass/watt. The range of aerosol produced on a per puff basis ranged from 1.5 to 28 mg, and, normalized for power applied to the coil, ranged from 0.27 to 1.1 mg/watt. Aerosol samples were also analyzed for the production of formaldehyde, acetaldehyde, and acrolein, as DNPH derivatives, at each power level. When reported on mass basis, three of the devices showed an increase in total aldehyde yield with increasing power applied to the coil, while two of the devices showed the opposite trend. The mass of formaldehyde, acetaldehyde, and acrolein produced per gram of total aerosol produced ranged from 0.01 to 73 mg/g, 0.006 to 5.8 mg/g, and