IgA nephropathy in association with Crohn's disease
IgA nephropathy in association with Crohn's disease
复制标题
DOI：
10.1007/s00384-004-0696-z
复制
发表时间：
2005-09-01
影响因子：
2.8
通讯作者：
Hennigan, TW
中科院分区：
文献类型：
--
作者：
Forshaw, MJ;Guirguis, O;Hennigan, TW
背景：炎症性肠病的泌尿系统并发症在高达25%的患者中可见，但肾实质疾病的报道很少。病例报告：作者描述了一例29岁男性回盲部克罗恩病的临床和放射学特征。他之前曾接受过无痛性肉眼血尿的检查，肾脏活检发现有IgA肾病。尽管接受了治疗，克罗恩病的定期加重与肾功能恶化和血尿的发展有关。患者最终接受了末端回肠和盲肠的手术切除。他的肾脏疾病在切除后的过去5年里一直处于静止状态。
Background: Urological complications of inflammatory bowel disease are seen in up to 25% of patients, but renal parenchymal disease is rarely reported. Case report: The authors describe a case of a 29-year-old man with clinical and radiological features of ileocaecal Crohn's disease. He had previously been investigated for painless macroscopic haematuria and a renal biopsy had revealed IgA nephropathy. Despite medical treatment, regular exacerbations of Crohn's disease were associated with deterioration in renal function and the development of haematuria. The patient eventually underwent surgical resection of the terminal ileum and caecum. His renal disease has remained quiescent for the last 5 years following resection.