Race, exercise training, and outcomes in chronic heart failure: Findings from Heart Failure - A Controlled Trial Investigating Outcomes in Exercise TraiNing (HF-ACTION)
Race, exercise training, and outcomes in chronic heart failure: Findings from Heart Failure - A Controlled Trial Investigating Outcomes in Exercise TraiNing (HF-ACTION)
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DOI：
10.1016/j.ahj.2013.06.002
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发表时间：
2013-09-01
影响因子：
4.8
通讯作者：
O'Connor, Christopher M.
中科院分区：
文献类型：
--
作者：
Mentz, Robert J.;Bittner, Vera;O'Connor, Christopher M.
背景种族强度作为当代慢性心力衰竭（HF）人群长期结局的独立预测因子及其与运动训练反应的相关性尚未得到很好的确立。我们的目的是调查种族和结果之间的关系，并探讨与运动训练在非卧床HF患者中的相互作用。方法我们进行了一项HF-ACTION分析，该分析将2331名具有射血分数的HF患者随机分组。结论慢性HF患者中的黑人与可改变的危险因素的患病率增加、运动能力降低和HF住院率增加相关，但没有增加死亡率或对运动训练的不同反应。
Background The strength of race as an independent predictor of long-term outcomes in a contemporary chronic heart failure (HF) population and its association with exercise training response have not been well established. We aimed to investigate the association between race and outcomes and to explore interactions with exercise training in patients with ambulatory HF.Methods We performed an analysis of HF-ACTION, which randomized 2331 patients with HF having an ejection fraction .5).Conclusions Black race in patients with chronic HF was associated with increased prevalence of modifiable risk factors, lower exercise performance, and increased HF hospitalization, but not increased mortality or a differential response to exercise training.