DIVERSE TRANSPOSABLE ELEMENTS ARE MOBILIZED IN HYBRID DYSGENESIS IN DROSOPHILA-VIRILIS
DIVERSE TRANSPOSABLE ELEMENTS ARE MOBILIZED IN HYBRID DYSGENESIS IN DROSOPHILA-VIRILIS
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DOI：
10.1073/pnas.92.17.8050
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发表时间：
1995-08-15
影响因子：
11.1
通讯作者：
LOZOVSKAYA, ER
中科院分区：
文献类型：
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作者：
PETROV, DA;SCHUTZMAN, JL;LOZOVSKAYA, ER
我们描述了果蝇 virilis 中的杂交发育不全系统，其中至少四个不相关的转座元件在基因不育杂交后全部被动员。这些数据在很大程度上与至少三个不同的杂交发育不全系统的叠加一致，每个系统都抑制不同的转座元件，这些转座元件在杂交后分解，可能是因为它们在宿主中共享共同的途径。这些数据也与一种机制一致，在该机制中，单个元素的动员可能通过染色体断裂来触发其他元素的动员。杂种发育不全中多种不相关元素的动员让人想起麦克林托克的证据 [McClintock, B. (1955) Brookhaven Symp.生物。 8, 58-74] 用于同时动员玉米中不同的转座元件。
We describe a system of hybrid dysgenesis in Drosophila virilis in which at least four unrelated transposable elements are all mobilized following a dysgenic cross. The data are largely consistent with the superposition of at least three different systems of hybrid dysgenesis, each repressing a different transposable element, which break down following the hybrid cross, possibly because they share a common pathway in the host. The data are also consistent with a mechanism in which mobilization of a single element triggers that of others, perhaps through chromosome breakage. The mobilization of multiple, unrelated elements in hybrid dysgenesis is reminiscent of McClintock's evidence [McClintock, B. (1955) Brookhaven Symp. Biol. 8, 58-74] for simultaneous mobilization of different transposable elements in maize.