Reliability and validity of quantifying absolute muscle hardness using ultrasound elastography.
Reliability and validity of quantifying absolute muscle hardness using ultrasound elastography.
复制标题
DOI：
10.1371/journal.pone.0045764
复制
发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Takahashi H
中科院分区：
文献类型：
--
作者：
Chino K;Akagi R;Dohi M;Fukashiro S;Takahashi H
肌肉硬度是代表横向肌肉刚度的机械特性。之前已经设计了一种使用超声弹性成像来量化绝对人体肌肉硬度的定量方法；但其可靠性和有效性尚未得到完全验证。本研究旨在验证该定量方法的可靠性和有效性。使用超声弹性成像对七种组织模拟材料（体外；杨氏模量范围，20-80 kPa；增量 10 kPa）和人类内侧腓肠肌（体内）的杨氏模量进行量化。根据两种参考材料（一种硬参考材料和一种软参考材料（杨氏模量分别为 7 和 30 kPa））的应变/杨氏模量比，计算了组织模拟材料和腓肠肌内侧肌的杨氏模量。该方法在研究者内部和研究者之间的可靠性得到了确认，其基础是从所有测量中获得的可接受的低变异系数（≤6.9%）和相当高的组内相关系数（≥0.77）。使用机械方法获得的模拟组织材料的杨氏模量与超声弹性成像之间的相关系数为0.996，与之前使用磁共振弹性成像获得的值相当。使用超声弹性成像获得的内侧腓肠肌杨氏模量在之前使用磁共振弹性成像获得的值范围内。验证了超声弹性成像测量绝对肌肉硬度定量方法的可靠性和有效性。
Muscle hardness is a mechanical property that represents transverse muscle stiffness. A quantitative method that uses ultrasound elastography for quantifying absolute human muscle hardness has been previously devised; however, its reliability and validity have not been completely verified. This study aimed to verify the reliability and validity of this quantitative method. The Young’s moduli of seven tissue-mimicking materials (in vitro; Young’s modulus range, 20–80 kPa; increments of 10 kPa) and the human medial gastrocnemius muscle (in vivo) were quantified using ultrasound elastography. On the basis of the strain/Young’s modulus ratio of two reference materials, one hard and one soft (Young’s moduli of 7 and 30 kPa, respectively), the Young’s moduli of the tissue-mimicking materials and medial gastrocnemius muscle were calculated. The intra- and inter-investigator reliability of the method was confirmed on the basis of acceptably low coefficient of variations (≤6.9%) and substantially high intraclass correlation coefficients (≥0.77) obtained from all measurements. The correlation coefficient between the Young’s moduli of the tissue-mimicking materials obtained using a mechanical method and ultrasound elastography was 0.996, which was equivalent to values previously obtained using magnetic resonance elastography. The Young’s moduli of the medial gastrocnemius muscle obtained using ultrasound elastography were within the range of values previously obtained using magnetic resonance elastography. The reliability and validity of the quantitative method for measuring absolute muscle hardness using ultrasound elastography were thus verified.
登录
查看更多内容
影响因子：
5
作者：
Friedrich-Rust, Mireen;Ong, Mei-Fang;Sarrazin, Christoph
通讯作者：
Sarrazin, Christoph
影响因子：
4.3
作者：
Basford, JR;Jenkyn, TR;Kaufman, KR
通讯作者：
Kaufman, KR
影响因子：
2.4
作者：
Gennisson, JL;Cornu, C;Portero, P
通讯作者：
Portero, P
影响因子：
56.9
作者：
MUTHUPILLAI, R;LOMAS, DJ;EHMAN, RL
通讯作者：
EHMAN, RL
影响因子：
3.3
作者：
Kawakami, Y;Ichinose, Y;Fukunaga, T
通讯作者：
Fukunaga, T