A Web-Based Exercise System (e-CuidateChemo) to Counter the Side Effects of Chemotherapy in Patients With Breast Cancer: Randomized Controlled Trial
A Web-Based Exercise System (e-CuidateChemo) to Counter the Side Effects of Chemotherapy in Patients With Breast Cancer: Randomized Controlled Trial
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DOI：
10.2196/14418
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发表时间：
2019-07-24
影响因子：
7.4
通讯作者：
Cantarero-Villanueva, Irene
中科院分区：
文献类型：
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作者：
Ariza-Garcia, Angelica;Arroyo-Morales, Manuel;Cantarero-Villanueva, Irene
背景资料：乳腺癌患者在化疗期间不得不面临高风险状态，这涉及其健康状况的恶化，包括广泛的身体恶化。面对面的体育锻炼计划在医疗期间的坚持率较低，远程医疗系统可以提高这些坚持率。结论：本文表明，基于网络的锻炼计划可以有效扭转因化疗而导致的功能能力和力量的损害。方法：共招募了68名诊断为乳腺癌并正在接受化疗的患者。患者分为两组：e-CuidateChemo（n = 34）和对照组（n = 34）。e-CuidateChemo组通过基于Web的系统参加了一个适应性的8周定制锻炼计划。由一名受过训练的盲态研究人员评估功能能力、力量、人体测量参数和身体成分。采用协方差分析和科恩d检验对干预效果进行检验。目的：评价网络健身计划的有效性结果：与对照组相比，e-CuidateChemo组的功能能力明显改善（6分钟步行试验：62.07 [SD 130.09] m vs-26.34 [SD 82.21] m; 6分钟步行试验%预测距离：10.81%[SD 22.69%] m vs-4.60%[SD 14.58%];组间效应：两者P = 0.015）。干预组还显示出显著改善的次要结局，如腹部手术的组间效应。（24.93 [SD 26.83] s vs-18.59 [SD 38.69] s），背部（12.45 [SD 10.20] kg vs 1.39 [10.72] kg）和下半身（-2.82 [SD 3.75] s vs 1.26 [SD 2.84] s）强度;所有P
Background: Breast cancer patients have to face a high-risk state during chemotherapy, which involves deterioration of their health including extensive physical deterioration. Face-to-face physical exercise programs have presented low adherence rates during medical treatment, and telehealth systems could improve these adherence rates.Conclusions: This paper showed that a Web-based exercise program was effective in reversing the detriment in functional capacity and strength due to chemotherapy.Methods: A total of 68 patients diagnosed with breast cancer, who were undergoing chemotherapy, were enrolled. The patients were categorized into two groups: e-CuidateChemo (n=34) and controls (n=34). The e-CuidateChemo group participated in an adapted 8-week tailored exercise program through a Web-based system. A blinded, trained researcher assessed functional capacity, strength, anthropometric parameters, and body composition. The intervention effects were tested using analysis of covariance and Cohen d tests.Objective: This study aimed to evaluate the effectiveness of a Web-based exercise program (e-CuidateChemo) to mitigate the side effects of chemotherapy on the physical being, anthropometric aspects, and body composition.Results: Functional capacity improved significantly in the e-CuidateChemo group compared to the control group (6-minute walk test: 62.07 [SD 130.09] m versus -26.34 [SD 82.21] m; 6-minute walk test % distance predicted: 10.81% [SD 22.69%] m versus -4.60% [SD 14.58%]; between-group effect: P=.015 for both). The intervention group also showed significantly improved secondary outcomes such as between-group effects for abdominal (24.93 [SD 26.83] s vs -18.59 [SD 38.69] s), back (12.45 [SD 10.20] kg vs 1.39 [10.72] kg), and lower body (-2.82 [SD 3.75] s vs 1.26 [SD 2.84] s) strength; all P