Rotavirus Disease in Guinea-Bissau, West Africa: A Review of Longitudinal Community and Hospital Studies
Rotavirus Disease in Guinea-Bissau, West Africa: A Review of Longitudinal Community and Hospital Studies
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DOI：
10.1086/653568
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发表时间：
2010-09-01
影响因子：
6.4
通讯作者：
Rodrigues, Amabelia
中科院分区：
文献类型：
--
作者：
Fischer, Thea Kolsen;Aaby, Peter;Rodrigues, Amabelia
轮状病毒是撒哈拉以南非洲儿童腹泻和死亡的最常见原因之一。本文综述了西非几内亚比绍的比绍以社区和医院为基础的轮状病毒病监测。在这里，轮状病毒感染呈现出季节性模式，每年的流行发生在1月至4月相对干燥和凉爽的月份，5月至12月登记的病例很少。大多数儿童（74%）在2岁之前经历首次感染，在2项涉及数百名儿童的大型前瞻性研究中，轮状病毒已被确定为所有病原体中致病性最高的病原体。
Rotavirus is one of the most common causes of childhood diarrheal disease and deaths in sub-Saharan Africa. This article reviews community- and hospital-based surveillance of rotavirus disease in Bissau, Guinea-Bissau, West Africa. Here, rotavirus infections exhibit a seasonal pattern, with annual epidemics occurring during the relatively dry and cooler months, from January to April, and few cases registered from May to December. Most children (74%) experience their first infection before the age of 2 years, and rotavirus has been identified as the most pathogenic of all diarrheal agents during 2 large prospective studies involving several hundred children 48 h after admission).